Which commonly prescribed is does the nurse identify as ototoxic?

Ondansetron and Metoclopramide

Aspirin and ibuprofen

Metoprolol and Furosemide

Pantoprazole Docusate Sodium

Answer and Explanation

The Correct Answer is B

A) Ondansetron and Metoclopramide:
Ondansetron is an antiemetic used to prevent nausea and vomiting, and Metoclopramide is a medication that promotes gastric emptying and is often used to treat nausea and gastroesophageal reflux. Neither of these medications are typically associated with ototoxicity. Ototoxicity is more commonly seen with medications that affect the inner ear or auditory pathways, particularly those that are used in high doses or over extended periods.

B) Aspirin and ibuprofen:
Both aspirin (a nonsteroidal anti-inflammatory drug, NSAID) and ibuprofen are associated with ototoxicity, especially when used in high doses or over prolonged periods. Ototoxicity from NSAIDs can result in symptoms such as tinnitus (ringing in the ears) or even hearing loss. This occurs due to their impact on the cochlea and auditory nerve.

C) Metoprolol and Furosemide:
Metoprolol is a beta-blocker used for managing hypertension, heart failure, and other cardiovascular conditions, and Furosemide is a diuretic often used to treat conditions such as heart failure and edema. Neither of these drugs is typically associated with ototoxicity. However, high doses of furosemide, particularly when given rapidly or intravenously, may be associated with transient hearing loss.

D) Pantoprazole and Docusate Sodium:
Pantoprazole is a proton pump inhibitor (PPI) used to treat gastrointestinal issues like acid reflux and ulcers. Docusate sodium is a stool softener used to treat constipation. Neither of these medications is known to cause ototoxicity. These drugs generally do not affect hearing or the auditory system.

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Correct Answer is C

Explanation

A) Equal but sluggishly reactive pupils:
Pupillary changes, including sluggish or unequal responses, are significant signs of increasing intracranial pressure (ICP) and should be monitored closely. However, altered level of consciousness (LOC) is typically one of the earliest signs of increased ICP. The response of the pupils to light can become abnormal later, once pressure increases within the brain, particularly when brainstem function is impacted.

B) Widening pulse pressure:
A widening pulse pressure is part of Cushing’s triad, which is a late sign of increased ICP. Cushing’s triad consists of hypertension, bradycardia, and irregular respirations (often seen as Cheyne-Stokes). These changes occur in the later stages of elevated ICP as a compensatory mechanism to preserve cerebral perfusion. While this is an important finding, altered LOC would precede the development of Cushing’s triad.

C) Altered level of consciousness:
Altered level of consciousness (LOC) is typically the first and most sensitive indicator of increased ICP. As pressure increases within the skull, it compresses brain tissue and affects the brainstem, which controls basic functions like consciousness. LOC can range from mild confusion and disorientation to full loss of consciousness or coma, depending on the severity of the ICP increase.

D) Tachycardia and hypotension:
Tachycardia and hypotension can be associated with shock or other conditions, but they are not characteristic of early increased ICP. In fact, as ICP rises, the body typically responds with bradycardia (slower heart rate) and hypertension (increased blood pressure), which are part of the compensatory mechanisms.

Correct Answer is ["2.5"]

Explanation

Ordered Dose: The doctor has prescribed Diltiazem at a rate of 2.5 mg per hour. This means the patient needs to receive 2.5 milligrams of Diltiazem every hour.

Medication Concentration: The medication is supplied as 125 mg of Diltiazem in 125 mL of fluid. This translates to a concentration of 1 mg of Diltiazem per 1 mL of solution.

Since the medication concentration is 1 mg/mL, delivering 2.5 mg of Diltiazem per hour requires infusing 2.5 mL of the solution per hour.

Therefore, the nurse should set the IV pump to deliver 2.5 mL/hr of the Diltiazem solution.

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Which commonly prescribed is does the nurse identify as ototoxic?

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Naxlex Comprehensive Predictor Exams

The nurse is caring for a patient with an acute head injury. Which assessment finding would first alert the nurse that the patient is developing an increase in intracranial pressure (ICP)?

Correct Answer is C

Explanation

A patient is to receive a continuous infusion of Diltiazem at 2.5 mg hr for Atrial fibrillation, The medication is supplied 125 mg of Diltlazem in 125 mL of IV fluid. At what rate should the nurse set the IV pump? (round to the nearest tenth)

Correct Answer is ["2.5"]

Explanation

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