Which cytotoxic lymphocyte granules contain serine proteases that induce apoptosis in target cells?
Perforins.
Cytokines.
Granzymes.
Interferons.
The Correct Answer is C
Granzymes are a family of serine proteases that are stored in and secreted from the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
They work in synergy with perforin, a pore-forming toxin, to induce apoptosis in target cells.
Perforin is necessary for the delivery of granzyme B to the target cell cytosol where caspase-dependent and -independent pathways to apoptosis are activated.
Perforins (choice A) are pore-forming toxins that work in synergy with granzymes to induce apoptosis in target cells.
Cytokines (choice B) are signaling molecules that regulate immune responses but do not directly induce apoptosis in target cells.
Interferons (choice D) are a type of cytokine that play a role in immune responses but do not directly induce apoptosis in target cells.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Using a placebo group and a double-blind technique for giving the medications is the best way to ensure that the study is valid and reliable.
A placebo group helps control for the placebo effect, which can influence the results of a study.
A double-blind technique means that neither the patients nor the researchers know which medication is being given, reducing bias.
Choice A is not the best answer because while a large sample size and standardized procedure can increase reliability, they do not address validity.
Choice C is not the best answer because a matched-pairs design and crossover technique are useful for reducing variability but do not address validity.
Choice D is not the best answer because a convenience sample may not be representative and a pretest-posttest design does not control for extraneous variables.
Correct Answer is B
Explanation
PCR (polymerase chain reaction) is a laboratory technique used to make many copies of a specific region of DNA.
The goal of PCR is to make enough of the target DNA region that it can be analyzed or used in some other way.
PCR has many research and practical applications, including DNA cloning, medical diagnostics, and forensic analysis of DNA.
Choice A is incorrect because PCR does not separate DNA fragments by size. Choice C is incorrect because PCR does not sequence DNA fragments.
Choice D is incorrect because PCR does not analyze protein expression levels.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.