Which hormone contributes to back pain by relaxing ligaments?
Estrogen
Progesterone
Relaxin
hCG
The Correct Answer is C
Relaxin in pregnancy is a peptide hormone that causes ligamentous relaxation, increased pelvic mobility, and reduced joint stability, contributing to back and pelvic pain. It is secreted mainly by the corpus luteum, decidua, and placenta, with peak levels in the first trimester. Normal physiologic effects include softening of the cervix and widening of the pubic symphysis to prepare for delivery. Excessive ligamentous laxity, however, decreases spinal and pelvic support, leading to musculoskeletal discomfort.
Rationale for correct answers
3. Relaxin specifically loosens pelvic ligaments and soft tissues, reducing stability of the sacroiliac joints and lumbar spine. This directly contributes to the back pain commonly reported in pregnancy.
Rationale for incorrect answers
1. Estrogen promotes uterine growth, vascular proliferation, and breast development. While it supports connective tissue changes, it is not the primary cause of ligamentous relaxation leading to back pain.
2. Progesterone relaxes smooth muscle, reducing uterine contractility and gastrointestinal motility, but it does not significantly relax ligaments in the spine or pelvis.
4. hCG maintains the corpus luteum in early pregnancy and supports progesterone secretion. It does not affect ligaments or musculoskeletal support, so it is not a cause of back pain.
Take home points
- Relaxin is the hormone responsible for ligament relaxation and joint laxity in pregnancy.
- Ligamentous laxity contributes to back pain and pelvic instability.
- Estrogen and progesterone affect uterine and vascular changes, not ligamentous support.
- Back pain in pregnancy must be differentiated from pathologic causes such as urinary tract infection or disc disease.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D"]
Explanation
Back pain in pregnancyarises from relaxin-induced ligament laxity, lumbar lordosis, and increased mechanical strainfrom fetal growth. Normal lumbar curvature increases as the uterus enlarges, shifting the center of gravity anteriorly. Relaxin loosens sacroiliac and pubic ligaments, decreasing joint stability. Risk is worsened by prolonged standing, poor posture, and reduced abdominal muscle tone. Management focuses on non-pharmacologic interventions to support the spine, relieve muscle strain, and improve posture.
Rationale for correct answers
1.Using a maternity belt supports the abdomen, redistributes weight, and reduces strain on lumbar muscles, effectively relieving back pain.
3.Practicing prenatal yoga improves posture, flexibility, and core strength, helping stabilize the spine and decrease musculoskeletal discomfort.
4.Applying heat therapy relaxes paraspinal muscles, reduces muscle spasm, and improves circulation, providing symptomatic relief for back pain.
Rationale for incorrect answers
2.Performing high-impact exercise increases mechanical strain and joint instability, worsening back pain. Safer options are low-impact activities such as swimming, walking, and prenatal yoga.
5.Prolonged standing aggravates venous stasis and lumbar strain, worsening discomfort instead of relieving it. Regular rest and position changes are recommended.
Take home points
- Back pain in pregnancy is caused by ligament laxity, lumbar lordosis, and increased load.
- Effective relief measures include maternity belts, prenatal yoga, and heat therapy.
- High-impact activity and prolonged standing worsen symptoms.
- Differential diagnoses include urinary tract infection and preterm labor, which can also present with back pain.
Correct Answer is ["A","B","D","E"]
Explanation
Heartburn in pregnancy(pyrosis) results from progesterone-induced relaxationof the lower esophageal sphincter, delayed gastric emptying, and mechanical pressurefrom the enlarging uterus. Gastric acid normally has a pH of 1.5–3.5, and disruption of esophageal sphincter tone allows reflux of this acidic content into the esophagus, producing burning retrosternal pain. Risk factors include large meals, lying supine after eating, fatty/spicy foods, and abdominal compression. Management emphasizes lifestyle and positional modifications.
Rationale for correct answers
1.Eating small, frequent meals prevents gastric overdistension, lowering reflux risk.
2.Avoiding spicy and fatty foods reduces gastric acid stimulation and delays gastric emptying, helping relieve symptoms.
4.Elevating the head of the bed during sleep decreases nocturnal reflux by using gravity to limit acid regurgitation.
5.Avoiding tight clothing around the abdomen reduces intra-abdominal pressure, lowering the chance of reflux.
Rationale for incorrect answers
3.Lying down immediately after eating worsens reflux because gravity no longer prevents acid regurgitation. Patients should wait at least 2–3 hours before lying down.
Take home points
- Heartburn in pregnancy is due to progesterone relaxation of the LES and uterine pressure.
- Small, frequent meals and avoidance of spicy/fatty foods help reduce reflux.
- Elevating the head of the bed prevents nocturnal symptoms.
- Tight abdominal clothing increases reflux risk and should be avoided.
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