Which of the choices below is NOT a glomerular filtration rate control method?
neural regulation
hormonal regulation
electrolyte levels
renal autoregulation
The Correct Answer is C
A. neural regulation: The sympathetic nervous system modulates the glomerular filtration rate during periods of extreme stress or blood loss. High levels of norepinephrine induce intense vasoconstriction of the afferent arterioles to divert blood to vital organs. This extrinsic control mechanism overrides local autoregulation to maintain systemic homeostasis and blood pressure.
B. hormonal regulation: The renin-angiotensin-aldosterone system and atrial natriuretic peptide serve as long-term chemical regulators of renal blood flow. Angiotensin 2 primarily constricts efferent arterioles to maintain pressure, while atrial natriuretic peptide increases the filtration rate by relaxing the mesangial cells. These hormones adjust the filtration surface area and capillary hydrostatic pressure.
C. electrolyte levels: While the concentration of specific ions like sodium triggers the macula densa, electrolyte levels themselves are the variables being regulated rather than the control method. The kidney adjusts the filtration rate to correct electrolyte imbalances, but the ions do not act as an independent regulatory system. This represents a physiological parameter rather than a control mechanism.
D. renal autoregulation: This intrinsic mechanism allows the kidneys to maintain a relatively constant filtration rate despite fluctuations in systemic arterial pressure. It involves the myogenic mechanism, which responds to vascular wall stretch, and tubuloglomerular feedback, which responds to filtrate chemistry. These local adjustments ensure stable renal function between mean arterial pressures of 80 and 180 mmHg.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. the clitoris: Both the penis and the clitoris originate from the same embryonic structure, the genital tubercle. They contain similar erectile tissues and sensory nerve endings, making them developmentally equivalent. This homology is a fundamental concept in the study of reproductive organ differentiation during embryogenesis.
B. the vagina: The vagina is the female copulatory organ and birth canal, which developmentally corresponds more closely to the male prostatic utricle. While it interacts with the penis during intercourse, it does not share the same embryonic precursor as the phallus. Its structural role and origin are distinct.
C. the cervix: The cervix is the inferior portion of the uterus that projects into the vaginal canal. It serves as a gateway for sperm and a protective barrier during pregnancy. It has no structural or developmental homology with the external genitalia of the male reproductive system.
D. the appendix: The vermiform appendix is a vestigial lymphoid organ attached to the cecum of the large intestine. It belongs to the digestive and immune systems rather than the reproductive system. There is no biological or embryonic relationship between the appendix and the male penis.
E. the urethra: While both males and females possess a urethra, it is a shared urinary structure rather than a homologous reproductive organ. In males, the urethra is much longer and carries semen, but the organ as a whole does not serve as a developmental counterpart to the penis.
Correct Answer is B
Explanation
A. hormones: Most small hormones, particularly steroid and peptide hormones not bound to large carrier proteins, are small enough to pass through the filtration membrane. They are often found in the initial filtrate in the capsular space. Their presence does not distinguish filtrate from plasma significantly.
B. plasma protein: The basement membrane and filtration slits are negatively charged and sized to repel large proteins like albumin. Consequently, the filtrate is essentially protein-free under normal conditions. The absence of these macromolecules is the primary chemical difference between plasma and glomerular filtrate.
C. glucose: Glucose is a small, uncharged molecule that moves freely across the filtration membrane into the capsular space. The concentration of glucose in the initial filtrate is identical to its concentration in the plasma. It is later reabsorbed entirely by the proximal convoluted tubules.
D. electrolytes: Ions such as sodium, potassium, and chloride are small enough to pass through the fenestrated capillaries and filtration slits without restriction. The electrolyte composition of the glomerular filtrate initially mirrors that of the blood plasma. Their balance is adjusted later during tubular processing.
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