Which of the following correctly describes the effects of sympathetic and parasympathetic stimulation on heart rate?
Sympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate.
Parasympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate.
Sympathetic stimulation releases norepinephrine (NE), which binds to muscarinic receptors, slowing heart rate.
Parasympathetic stimulation releases acetylcholine (ACh), which binds to the beta-1 receptors, increasing heart rate.
The Correct Answer is A
A. Sympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate: Sympathetic nerve fibers release norepinephrine, which binds to beta-1 adrenergic receptors on the sinoatrial node and ventricular myocardium. This increases the rate of depolarization in pacemaker cells, enhancing heart rate (positive chronotropy), and also increases contractility (positive inotropy), preparing the heart for increased cardiac output.
B. Parasympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate: Parasympathetic fibers do not release norepinephrine; they release acetylcholine. Norepinephrine is specific to sympathetic innervation. Therefore, this description incorrectly attributes sympathetic neurotransmission to parasympathetic activity.
C. Sympathetic stimulation releases norepinephrine (NE), which binds to muscarinic receptors, slowing heart rate: Muscarinic receptors are activated by acetylcholine released from parasympathetic fibers, not by norepinephrine. Sympathetic stimulation increases heart rate, rather than slowing it, through beta-1 receptor activation.
D. Parasympathetic stimulation releases acetylcholine (ACh), which binds to the beta-1 receptors, increasing heart rate: Parasympathetic stimulation releases acetylcholine, but it binds to muscarinic receptors on pacemaker cells, not beta-1 adrenergic receptors. Activation of muscarinic receptors slows the heart rate (negative chronotropy) rather than increasing it.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is {"dropdown-group-1":"A"}
Explanation
Correct answer: Left coronary
The left coronary artery arises from the left side of the ascending aorta, just above the aortic valve, and quickly branches to supply the heart muscle. Its two main branches are the anterior interventricular artery (also called the left anterior descending artery), which runs along the interventricular groove supplying the anterior walls of both ventricles, and the circumflex artery, which curves around the left side of the heart to supply the lateral and posterior walls of the left ventricle and left atrium. This anatomical arrangement ensures that oxygen-rich blood from the aorta is delivered efficiently to the majority of the left heart myocardium.
Correct Answer is B
Explanation
A. Higher pressure in the atria than in the veins: While venous return contributes to atrial filling, blood flow from the atria into the ventricles during diastole is primarily driven by pressure gradients between the atria and ventricles, not just between veins and atria. Venous pressure alone does not account for the efficient filling of the ventricles.
B. Contraction of the atria: During atrial systole, the atria contract, increasing atrial pressure above ventricular pressure. This pressure gradient forces blood through the open atrioventricular valves (tricuspid and mitral) into the ventricles, completing the final phase of ventricular filling known as the “atrial kick,” which contributes approximately 20–30% of ventricular end-diastolic volume.
C. Higher pressure in the veins than in the atria: Although venous pressure drives passive filling of the atria, the actual movement of blood into the ventricles requires the atria to generate pressure higher than that in the relaxed ventricles. Without atrial contraction, ventricular filling would rely solely on passive flow, which is less efficient.
D. Contraction of the ventricles: Ventricular contraction occurs during systole, when ventricular pressure rises above atrial pressure. This causes the atrioventricular valves to close, preventing backflow into the atria. Ventricular contraction does not facilitate blood flow from atria to ventricles; it actually temporarily halts it.
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