Which of the following correctly describes the effects of sympathetic and parasympathetic stimulation on heart rate?
Sympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate.
Parasympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate.
Sympathetic stimulation releases norepinephrine (NE), which binds to muscarinic receptors, slowing heart rate.
Parasympathetic stimulation releases acetylcholine (ACh), which binds to the beta-1 receptors, increasing heart rate.
The Correct Answer is A
A. Sympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate: Sympathetic nerve fibers release norepinephrine, which binds to beta-1 adrenergic receptors on the sinoatrial node and ventricular myocardium. This increases the rate of depolarization in pacemaker cells, enhancing heart rate (positive chronotropy), and also increases contractility (positive inotropy), preparing the heart for increased cardiac output.
B. Parasympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate: Parasympathetic fibers do not release norepinephrine; they release acetylcholine. Norepinephrine is specific to sympathetic innervation. Therefore, this description incorrectly attributes sympathetic neurotransmission to parasympathetic activity.
C. Sympathetic stimulation releases norepinephrine (NE), which binds to muscarinic receptors, slowing heart rate: Muscarinic receptors are activated by acetylcholine released from parasympathetic fibers, not by norepinephrine. Sympathetic stimulation increases heart rate, rather than slowing it, through beta-1 receptor activation.
D. Parasympathetic stimulation releases acetylcholine (ACh), which binds to the beta-1 receptors, increasing heart rate: Parasympathetic stimulation releases acetylcholine, but it binds to muscarinic receptors on pacemaker cells, not beta-1 adrenergic receptors. Activation of muscarinic receptors slows the heart rate (negative chronotropy) rather than increasing it.
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Naxlex Comprehensive Predictor Exams
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Correct Answer is {"dropdown-group-1":"D","dropdown-group-2":"E","dropdown-group-3":"B","dropdown-group-4":"A","dropdown-group-5":"C"}
Explanation
Correct answer:
- A cluster of cells located in the interatrial septum that delays the electrical signal before it passes to the ventricles: Atrioventricular node
- The pacemaker of the heart, located in the right atrium, responsible for initiating the heartbeat: Sinoatrial node
- The valve located between the right atrium and right ventricle: Tricuspid valve
- The layer of the pericardium that covers the heart directly, also known as the epicardium: Visceral pericardium
- Blood vessels carrying oxygenated blood from the lungs to the left atrium: Pulmonary veins
• Atrioventricular node: The AV node is located in the interatrial septum and functions to delay the electrical impulse received from the SA node. This delay allows the atria to contract and complete ventricular filling before ventricular contraction. Its position and timing role are crucial for coordinated cardiac conduction.
• Sinoatrial node: The SA node, located in the right atrium near the superior vena cava, acts as the heart’s natural pacemaker. It generates electrical impulses that initiate each heartbeat, setting the rhythm for the entire heart. Proper SA node function is essential for synchronized atrial and ventricular activity.
• Tricuspid valve: The tricuspid valve sits between the right atrium and right ventricle, preventing backflow of blood during ventricular contraction. Its three leaflets open during diastole to allow atrial emptying into the ventricle. Proper valve function maintains unidirectional blood flow and cardiac efficiency.
• Visceral pericardium: Also called the epicardium, this layer of the pericardium lies directly on the heart surface. It provides protection, reduces friction during heartbeats, and contains blood vessels supplying the myocardium. Its anatomical position distinguishes it from the parietal pericardium.
• Pulmonary veins: Pulmonary veins carry oxygen-rich blood from the lungs to the left atrium. They are unique among veins as they transport oxygenated rather than deoxygenated blood. Their flow ensures that systemic circulation receives oxygenated blood.
Correct Answer is A
Explanation
A. They detect changes in position and movement during physical activity: Proprioceptors are sensory receptors located in muscles, tendons, and joints that detect body position, stretch, and movement. During physical activity, they provide the cardiovascular control centers in the medulla oblongata with information about muscle activity. This contributes to increases in heart rate and cardiac output, helping to meet the metabolic demands of exercising tissues.
B. They monitor blood pressure in the arteries: Blood pressure is monitored by baroreceptors, not proprioceptors. Baroreceptors, located in the carotid sinus and aortic arch, detect changes in arterial wall stretch and send signals to the cardiovascular centers to adjust heart rate, stroke volume, and vascular tone accordingly.
C. They detect chemical changes in the blood: Chemoreceptors, such as those in the carotid and aortic bodies, sense changes in oxygen, carbon dioxide, and pH levels in the blood. They modulate heart rate and respiratory activity, but this is a separate mechanism from proprioceptor input.
D. They monitor heart rate directly: Heart rate is regulated by autonomic input from the sympathetic and parasympathetic nervous systems, influenced by sensory information from baroreceptors, chemoreceptors, and proprioceptors indirectly. Proprioceptors do not directly monitor the heart rate itself.
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