Which of the following correctly describes the effects of sympathetic and parasympathetic stimulation on heart rate?
Sympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate.
Parasympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate.
Sympathetic stimulation releases norepinephrine (NE), which binds to muscarinic receptors, slowing heart rate.
Parasympathetic stimulation releases acetylcholine (ACh), which binds to the beta-1 receptors, increasing heart rate.
The Correct Answer is A
A. Sympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate: Sympathetic nerve fibers release norepinephrine, which binds to beta-1 adrenergic receptors on the sinoatrial node and ventricular myocardium. This increases the rate of depolarization in pacemaker cells, enhancing heart rate (positive chronotropy), and also increases contractility (positive inotropy), preparing the heart for increased cardiac output.
B. Parasympathetic stimulation releases norepinephrine (NE), which binds to beta-1 receptors, increasing heart rate: Parasympathetic fibers do not release norepinephrine; they release acetylcholine. Norepinephrine is specific to sympathetic innervation. Therefore, this description incorrectly attributes sympathetic neurotransmission to parasympathetic activity.
C. Sympathetic stimulation releases norepinephrine (NE), which binds to muscarinic receptors, slowing heart rate: Muscarinic receptors are activated by acetylcholine released from parasympathetic fibers, not by norepinephrine. Sympathetic stimulation increases heart rate, rather than slowing it, through beta-1 receptor activation.
D. Parasympathetic stimulation releases acetylcholine (ACh), which binds to the beta-1 receptors, increasing heart rate: Parasympathetic stimulation releases acetylcholine, but it binds to muscarinic receptors on pacemaker cells, not beta-1 adrenergic receptors. Activation of muscarinic receptors slows the heart rate (negative chronotropy) rather than increasing it.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
N: Pulmonary valve- The pulmonary valve is a semilunar valve between the right ventricle and pulmonary artery. It prevents backflow into the ventricle during diastole, facilitating blood flow toward the lungs for oxygenation.
E: Fossa ovalis - The fossa ovalis is a shallow, thumb-sized depression located in the interatrial septum (the wall separating the right and left atria). In a developing fetus, the foramen ovale is an open "tunnel" that allows blood to bypass the lungs by flowing directly from the right atrium to the left atrium. Once a baby takes their first breath, the pressure changes in the heart cause a flap of tissue to close over this opening. Over time, it fuses shut, leaving behind the shallow indensee fossa ovalis.
O: chordae tendinae: Chordae tendineae are fibrous cords connecting the atrioventricular valve leaflets (mitral and tricuspid) to papillary muscles. They prevent valve prolapse during ventricular contraction, ensuring unidirectional blood flow.
J: Aortic arch- The aortic arch is the curved portion of the aorta that distributes oxygenated blood from the left ventricle to systemic arteries. It contains baroreceptors and helps regulate blood pressure.
Correct Answer is A
Explanation
Correct answer: True
The endocardium is a thin, smooth membrane that lines the internal chambers of the heart, including the atria, ventricles, and heart valves. It is composed of endothelial cells and connective tissue, providing a non-thrombogenic surface that minimizes friction as blood flows through the heart. The endocardium plays a critical role in maintaining efficient circulation, regulating myocardial function, and forming the inner lining of the heart valves to ensure unidirectional blood flow. Its anatomical location within the heart chambers allows it to serve as a protective barrier between the blood and the myocardium, supporting both structural integrity and optimal cardiac performance.
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