As soon as an invader, known as a(n) _____, enters the body, the body begins to fight.

There are two major types of receptor molecules that respond to an intercellular chemical signal:

• Intracellular receptors: These receptors are located in either the cytoplasm or the nucleus of the cell. Signals diffuse across the cell membrane and bind to the receptor sites on intracellular receptors, of the same cell.
• Membrane-bound receptors: These receptors extend across the cell membrane, with their receptor sites on the outer surface of the cell membrane. They respond to intercellular chemical signals that are large, water-soluble molecules that do not diffuse across the cell membrane.

Mendel developed theories of genetics that scientists around the world use today.

From experiments with garden peas, Mendel developed a simple set of rules that accurately predicted patterns of heredity. He discovered that plants eitherself-pollinateorcross-pollinate, when the pollen from one plant fertilizes the pistil of another plant. He also discovered that traits are eitherdominantorrecessive. Dominant traits are expressed, and recessive traits are hidden.

Mendel’s Theory of Heredity

To explain his results, Mendel proposed a theory that has become the foundation of the science of genetics. The theory has five elements:

• Parents do not transmit traits directly to their offspring. Rather, they pass on units of information calledgenes.
• For each trait, an individual has two factors: one from each parent. If the two factors have the same information, the individual ishomozygousfor that trait. If the two factors are different, the individual isheterozygousfor that trait. Each copy of a factor, orgene, is called anallele.
• The alleles determine the physical appearance, orphenotype. The set of alleles an individual has is itsgenotype.
• An individual receives one allele from each parent.
• The presence of an allele does not guarantee that the trait will be expressed.

Taxonomy is the process of classifying, describing, and naming organisms. There are seven levels in the Linnaean taxonomic system, starting with the broadest level, kingdom, and ending with the species level. For example, in the image the genus level contains two types of bears, but the species level shows one type. Additionally,organisms in each level are found in the level above it. For example, organisms in the order level are part of the class level. This classification system is based on physical similarities across living things. It does not account for molecular or genetic similarities.

The autonomic nervous systemis responsible for activities that arenonvoluntaryand under unconscious control. This system controls glands and the smooth muscles of internal organs, heart rate, breathing, and digestion. The autonomic nervous system is further divided into the following:

• Sympathetic nervous system: The sympathetic nervous system focuses on emergency situations by preparing the body forfight or flight. (Sympathetic = Stress)
• Parasympathetic nervous system: The parasympathetic nervous system controls involuntary processes unrelated to emergencies. This system deals with “rest or digest” activities. (Parasympathetic = Peace)

Thesomatic nervous systemprimarily controlsvoluntaryactivities such as walking and riding a bicycle. Thus, this system sends information to the CNS and motor nerve fibers that are attached to skeletal muscle.

In solids, particles are usually closer together than in other states of matter because of the strong cohesive forces between the particles.

• Solids, liquids, gases, and plasmas differ from one another in the amount of energy that the particles have and the strength of the cohesive forces that hold the particles together.
• Cohesion is the tendency of particles of the same kind to stick to each other.
• A solid has the lowest amount of energy because its particles are packed close together. Liquids have more energy than a solid, and gases have more energy than solids or liquids because the cohesive forces are very weak.

A cell copies its DNA during the S phase, and nucleotides are the building blocks of DNA. Thus, the step preceding the S phase, theG1phase, is the phase of the cell cycle when the cell would contain the most nucleotides.

For a cell to divide into more cells, it must grow, copy its DNA, and produce new daughter cells. Thecell cycleregulates cellular division. This process can either prevent a cell from dividing or trigger it to start dividing.

The cell cycle is an organized process divided into two phases:interphaseand theM (mitotic) phase. During interphase, the cell grows and copies its DNA. After the cell reaches the M phase, division of the two new cells can occur. The G1, S, and G2phases make up interphase.

• G1:The first gap phase, during which the cell prepares to copy its DNA
• S:The synthesis phase, during which DNA is copied
• G2:The second gap phase, during which the cell prepares for cell division

It may appear that little is happening in the cell during the gap phases. Most of the activity occurs at the level of enzymes and macromolecules. The cell produces things like nucleotidesfor synthesizing new DNA strands, enzymes for copying the DNA, and tubulin proteins for building the mitotic spindle. During the S phase, the DNA in the cell doubles, but few other signs are obvious under the microscope. All the dramatic events that can be seen under a microscope occur during the M phase: the chromosomes move, and the cell splits into two new cells with identical nuclei.

If the cohesion between particles decreases, then the particles must be undergoing a phase change that allows particles to move farther apart. This happens when a substance vaporizes and turns from liquid to gas. Any phase change that moves to the right in the diagram above requires energy to be added to the system because the substance has more energy at the end of the phase change. The phase changes aremelting,vaporization (boiling), andsublimation. When energy is added, particles move faster and can break away from each other more easily as they move to a state of matter with a higher amount of energy. This is most commonly done by heating the substance.

A control group is a factor that does not change during an experiment. Due to this, it is used as a standard for comparison with variables that do change such as a dependent variable.

Recall that these make up thescientific method,described below:

• Problem:The question created because of an observation.Example: Does the size of a plastic object affect how fast it naturally degrades in a lake?
• Research:Reliable information available about what is observed.Example: Learn how plastics are made and understand the properties of a lake.
• Hypothesis:A predicted solution to the question or problem.Example: If the plastic material is small, then it will degrade faster than a large particle.
• Experiment:A series of tests used to evaluate the hypothesis. Experiments consist of anindependent variablethat the researcher modifies and adependent variablethat changes due to the independent variable. They also include acontrol groupused as a standard to make comparisons.
  • Example: Collect plastic particles both onshore and offshore of the lake over time. Determine the size of the particles and describe the lake conditions during this time period.
• Observe:Analyze data collected during an experiment to observe patterns.
  • Example: Analyze the differences between the numbers of particles collected in terms of size.
• Conclusion:State whether the hypothesis is rejected or accepted and summarize all results.
• Communicate:Report findings so others can replicate and verify the results.

Pathogenis an infectious foreign body that enters the body and causes disease or illness to the person. There are five types of pathogens: viruses, bacteria, fungi, protozoa, and worms. Pathogens have antigen proteins found on their surface and are unique to each pathogen.

Antibodyis a protein produced by the body’s immune system when it detects harmful substances (antigens). There are many different antibodies found in the body. Each one is unique and protects the body against the specific antigen that it detects at any given time. If there are no antibodies for a specific antigen, the more likely you are to develop an illness.

Vaccinationsare the introduction of a dead or disabled pathogen or of a harmless microbe with the protein of a pathogen on its surface into the body. Often administered through needle injection, to stimulate the immune system to produce immunity to a specific disease Immunity protects the body from a disease when exposed to it.

There are four types of immunity: natural/passive, natural/active, artificial/passive, and artificial/ active.

• Natural/passive – Babies receive immunities from breastmilk.
• Natural/active – The body produces antibodies to combat an illness when a person becomes sick.
• Artificial/passive – This immunity is temporary and requires doses of serum to maintain the immunity.
• Artificial/active – A vaccination provides artificial/active immunity.

The sequence of amino acids in a gene determines the primary structure of a protein. The components necessary fortranslationare located in the cytoplasm. Translation is the making of proteins by mRNA binding to a ribosome with the start codon that initiates the production of amino acids. Apeptide bondforms and connects the amino acids together. The sequence of amino acids determines the protein’s structure, which determines its function.