What is the name of the genetic disorder caused by the presence of an extra chromosome 21?
Turner syndrome
Klinefelter syndrome
Down syndrome
Huntington's disease
Correct Answer : C
Down syndrome is a genetic disorder caused by the presence of an extra copy of chromosome 21. It is also known as trisomy 21, because affected individuals have three copies of chromosome 21 instead of the normal two.
The extra chromosome 21 in Down syndrome occurs due to a random error in cell division, which leads to the production of an abnormal gamete (egg or sperm) with an extra copy of the chromosome. When this gamete fuses with a normal gamete during fertilization, the resulting zygote has 47 chromosomes instead of the usual 46, and develops into a fetus with Down syndrome.
Down syndrome is characterized by a range of physical and intellectual symptoms, including developmental delays, intellectual disability, distinctive facial features, heart defects, and increased risk of certain medical conditions such as leukemia and Alzheimer's disease. However, the severity and expression of these symptoms can vary widely among affected individuals.
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Correct Answer is D
Explanation
A double-blind study is a research design in which neither the participants nor the researchers know which group participants are assigned to. This is done to minimize bias and ensure that the results of the study are as objective as possible. In a double-blind study, the treatment and control groups are randomly assigned, and the participants and researchers are unaware of which group each participant is assigned to.
Option a) is an example of a randomized controlled trial, which is a common research design, but it is not necessarily double-blind.
Option b) is an example of an open-label study, in which both the participants and the researchers know which group each participant is assigned to.
Option c) is an example of a single-blind study, in which the participants do not know which group they are assigned to, but the researchers do.
Correct Answer is A
Explanation
A physical change is a change that affects the physical properties of a substance, but does not change its chemical identity. Physical changes include changes in state, such as melting or boiling, changes in shape or size, and changes in phase, such as the dissolution of a solid in a liquid.
A chemical change, on the other hand, is a change that results in the formation of new substances with different chemical properties. Chemical changes involve the breaking of chemical bonds between atoms and the formation of new bonds to create new compounds. Chemical changes are usually accompanied by a change in color, the formation of a gas or a solid, or the release or absorption of energy.
Overall, the main difference between a physical change and a chemical change is that a physical change only affects the physical properties of a substance while a chemical change results in the formation of new substances with different chemical properties.
Note:Choice B is partially cirrect since physical changes can involve changes in the state of matter (e.g., ice melting into water), but it's not the main characteristic. A chemical change typically involves the change of one substance into another with different chemical properties.
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Correct Answer is A
Explanation
The scientific method is a systematic approach used to answer questions or test hypotheses about the natural world. The steps involved in the scientific method are:
- Observation: This is the first step in the scientific method. It involves observing a phenomenon or a problem and gathering information about it.
- Hypothesis: After making an observation, a scientist forms a hypothesis, which is a tentative explanation for the phenomenon or problem.
3. Prediction: Based on the hypothesis, the scientist makes a prediction about what will happen in an experiment or what they will observe.
4. Experimentation: The scientist designs and conducts an experiment to test the hypothesis and prediction.
5. Analysis: The data collected from the experiment are analyzed to determine if they support or refute the hypothesis.
6. Conclusion: Based on the analysis of the data, the scientist draws a conclusion about whether the hypothesis is supported or refuted.
Option b) is incorrect because it starts with hypothesis before observation. Option c) is incorrect because prediction comes before experimentation. Option d) is incorrect because hypothesis comes after observation and data collection.
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Correct Answer is C
Explanation
One of the main funcons of the respiratory system is to facilitate the exchange of gases between the body and the environment. During inhalaon, air enters the lungs and oxygen is absorbed into the bloodstream. During exhalaon, carbon dioxide is removed from the body and expelled into the environment.
Correct Answer is C
Explanation
A frameshift mutation is a type of genetic mutation that involves the insertion or deletion of one or more nucleotides in a DNA sequence. This can cause a shift in the reading frame of the genetic code, resulting in a change in the amino acid sequence of the resulting protein. Frameshift mutations can have significant effects on the function of the protein and can lead to genetic disorders or diseases.
Correct Answer is D
Explanation
- A. Nanolitres (nL) → Extremely small unit (1 nL = 0.000000001 L), used for microscopic measurements. ❌
- B. Microlitres (µL) → Also very small (1 µL = 0.000001 L), used in lab settings. ❌
- C. Litres (L) → Too large, as typical urine output per hour is much less than 1 L. ❌
- D. Millilitres (mL) → Suitable, since normal urine output per hour is about 30-80 mL. ✅
Correct Answer is A
Explanation
Insulin is a hormone produced by the pancreas that plays a crucial role in regulating the levels of glucose (sugar) in the blood. After a person eats a meal, the levels of glucose in the blood rise, which stimulates the pancreas to release insulin into the bloodstream. Insulin acts on various cells in the body, particularly those in the liver, muscles, and adipose tissue, to promote the uptake, use, and storage of glucose.
Insulin helps to lower the levels of glucose in the blood by increasing the uptake of glucose by cells, stimulating the liver and muscle cells to store glucose in the form of glycogen, and inhibiting the production and release of glucose by the liver. This process is known as glucose homeostasis, and it helps to keep the levels of glucose in the blood within a normal range.
Deficiencies or abnormalities in insulin production or function can lead to a range of metabolic disorders, including type 1 and type 2 diabetes. In type 1 diabetes, the body does not produce enough insulin, while in type 2 diabetes, the body becomes resistant to the effects of insulin, leading to elevated levels of glucose in the blood.
Correct Answer is A
Explanation
The main difference between a solid and a liquid is their physical state and the way their particles are arranged. In a solid, the particles are tightly packed together and have a fixed position, which gives the solid a definite shape and volume. Solids are also characterized by their high density, low compressibility, and high thermal conductivity.
In contrast, the particles in a liquid are more loosely packed and can move around each other, which allows the liquid to take the shape of its container. Liquids have a definite volume but no fixed shape, which means they can be poured or spilled. Liquids also have a lower density than solids, are more compressible than solids, and have lower thermal conductivity than solids.
Option b) is incorrect because it describes the properties of a gas, not a liquid. Option c) is incorrect because solids and liquids have different physical properties. Option d) is incorrect because it describes the properties of a gas, not a liquid or a solid.
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Correct Answer is A
Explanation
The kidneys secrete a number of hormones, which are important for normal functioning of the body.
If blood pressure falls, renin is secreted by the kidneys to constrict the small blood vessels, thereby increasing blood pressure. If the kidneys aren’t functioning correctly, too much renin can be produced, increasing blood pressure and sometimes resulting in hypertension (high blood pressure). This is why a number of people with kidney diseases also have high blood pressure.
Correct Answer is B
Explanation
Transcription is the process by which DNA is copied into RNA. During transcription, the DNA molecule unwinds and RNA polymerase reads the DNA sequence and synthesizes a complementary RNA molecule using the DNA as a template.
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