What is the name of the genetic disorder caused by the presence of an extra chromosome 21?

The epididymis is a coiled tube located at the back of each testicle where the sperm mature and are stored until ejaculation. Sperm are produced in the testes and then transported to the epididymis where they undergo maturation and become motile. The epididymis provides a protective environment for the sperm, allowing them to mature and become more resilient to external stressors. During ejaculation, the sperm are transported from the epididymis to the vas deferens and then to the urethra for ejaculation.

The three major pairs of salivary glands are the parod glands, sublingual glands, and submandibular glands. The parotid glands are located just in front of your ears. The sublingual glands are below either side of your tongue, under the floor of your mouth. The submandibular glands are located below your jaw ¹.

Transfer RNA (tRNA) is a type of RNA molecule that carries amino acids to the ribosome during protein synthesis. Each tRNA molecule has a specific sequence of three nucleotides called an anticodon, which pairs with a complementary codon in the messenger RNA (mRNA) sequence. Each tRNA also carries a specific amino acid that corresponds to the codon it recognizes, allowing the ribosome to link the amino acids together in the correct order to form a protein.

In contrast, messenger RNA (mRNA) carries the genetic information from the DNA to the ribosome, where it serves as a template for protein synthesis. Ribosomal RNA (rRNA) is a component of the ribosome itself, where it helps to catalyze the formation of peptide bonds between amino acids. Small nuclear RNA (snRNA) is involved in splicing of pre-mRNA molecules during post-transcriptional processing.

Down syndrome is a genetic disorder caused by the presence of an extra copy of chromosome 21. It is also known as trisomy 21, because affected individuals have three copies of chromosome 21 instead of the normal two.

The extra chromosome 21 in Down syndrome occurs due to a random error in cell division, which leads to the production of an abnormal gamete (egg or sperm) with an extra copy of the chromosome. When this gamete fuses with a normal gamete during fertilization, the resulting zygote has 47 chromosomes instead of the usual 46, and develops into a fetus with Down syndrome.

Down syndrome is characterized by a range of physical and intellectual symptoms, including developmental delays, intellectual disability, distinctive facial features, heart defects, and increased risk of certain medical conditions such as leukemia and Alzheimer's disease. However, the severity and expression of these symptoms can vary widely among affected individuals.

• A. Nanolitres (nL) → Extremely small unit (1 nL = 0.000000001 L), used for microscopic measurements. ❌
• B. Microlitres (µL) → Also very small (1 µL = 0.000001 L), used in lab settings. ❌
• C. Litres (L) → Too large, as typical urine output per hour is much less than 1 L. ❌
• D. Millilitres (mL) → Suitable, since normal urine output per hour is about 30-80 mL. ✅

The vertebral column, also known as the spine or spinal column, is a series of bones called vertebrae that extend from the skull to the pelvis. It provides support for the body and protects the spinal cord. The five regions of the vertebral column, starting from the top and moving downwards, are:

1. Cervical: This region is made up of seven vertebrae and is located in the neck. The first two cervical vertebrae, the atlas and the axis, are specialized to allow for head movement.

2. Thoracic: This region is made up of twelve vertebrae and is located in the upper and middle back. The thoracic vertebrae are larger than the cervical vertebrae and articulate with the ribs.

3. Lumbar: This region is made up of five vertebrae and is located in the lower back. The lumbar vertebrae are the largest and strongest of the vertebrae.

4. Sacral: This region is made up of five fused vertebrae and is located in the pelvis. The sacrum forms the posterior wall of the pelvis and articulates with the hip bones.

5. Coccygeal: This region is made up of four fused vertebrae and is located at the base of the vertebral column. The coccyx, or tailbone, provides atachment points for muscles and ligaments.

The molecular geometry of a molecule of sulphur dioxide (SO2) is bent or V-shaped. This is because of the presence of two lone pairs on the sulfur atom, which cause repulsion and distort the bond angles in the molecule.

SO2 has a central sulfur atom bonded to two oxygen atoms by double bonds. The two double bonds and the two lone pairs of electrons on sulfur result in a trigonal planar arrangement of electron pairs around the sulfur atom. However, the repulsion between the lone pairs causes the two oxygen atoms to be pulled closer together, resulting in a bent or V-shaped molecular geometry.

The bent molecular geometry of SO2 affects its properties, such as its polarity and reactivity. SO2 is a polar molecule due to the asymmetric distribution of electrons, which results in a partial positive charge on the sulfur atom and partial negative charges on the oxygen atoms. This polarity makes SO2 a good solvent and reactant in chemical reactions, as well as a contributor to air pollution and acid rain.

Red blood cells, also known as erythrocytes, play a crucial role in the circulatory system, primarily by facilitating the transportation of oxygen to body tissues. The other choices are also explained below:

A. Facilitation of gas exchange in the alveoli: While gas exchange occurs in the alveoli of the lungs, it is primarily carried out by the respiratory system and involves the exchange of oxygen and carbon dioxide between air and blood. Red blood cells do not directly participate in this process.

B. Regulation of blood pH through the release of bicarbonate ions: The regulation of blood pH is mainly maintained by the bicarbonate buffering system, which involves the action of the respiratory and renal systems. Red blood cells do play a minor role in transporting carbon dioxide, which can indirectly influence pH, but it's not their primary function.

D. Synthesis of clotting factors in response to vascular injury: Clotting factors are primarily produced by the liver and are involved in the blood clotting process to prevent excessive bleeding. Red blood cells are not directly responsible for synthesizing these factors.

• The image shown is a highly detailed 3D surface view of a blood clot, which suggests that it was captured using a scanning electron microscope (SEM).
• SEM produces high-resolution, three-dimensional images by scanning a sample with a focused beam of electrons, making it ideal for studying surface structures like blood cells and clots.

Analysis of Other Options:

• A. Compound Light Microscope → Uses visible light to magnify samples but lacks the resolution and 3D detail seen in the image. ❌
• B. Transmission Electron Microscope (TEM) → Produces 2D images of ultra-thin sections, not detailed 3D surface views. ❌
• D. Stereoscope → A low-magnification microscope used for viewing larger objects, not detailed cellular structures. ❌

A frameshift mutation is a type of genetic mutation that involves the insertion or deletion of one or more nucleotides in a DNA sequence. This can cause a shift in the reading frame of the genetic code, resulting in a change in the amino acid sequence of the resulting protein. Frameshift mutations can have significant effects on the function of the protein and can lead to genetic disorders or diseases.