Where is skeletal muscle found?

The cardiovascular system is closely associated with hematopoiesis because it includes the heart and blood vessels, which are responsible for circulating blood throughout the body. Hematopoiesis, the process of blood cell formation, primarily occurs in the bone marrow, which is part of the skeletal system. However, the cardiovascular system plays a crucial role in transporting these blood cells to various parts of the body once they are produced in the bone marrow.

So, while the skeletal system provides the site for hematopoiesis, the cardiovascular system is responsible for distributing the blood cells, making it the most closely associated system in this context.

There are two major types of receptor molecules that respond to an intercellular chemical signal:

• Intracellular receptors: These receptors are located in either the cytoplasm or the nucleus of the cell. Signals diffuse across the cell membrane and bind to the receptor sites on intracellular receptors, of the same cell.
• Membrane-bound receptors: These receptors extend across the cell membrane, with their receptor sites on the outer surface of the cell membrane. They respond to intercellular chemical signals that are large, water-soluble molecules that do not diffuse across the cell membrane.

Theaging processaffects hormone activity in one of three ways: their secretion can decrease, remain unchanged, or increase.

Hormones thatdecrease secretioninclude the following:

• Estrogen (in women)
• Testosterone (in men)
• Growth hormone
• Melatonin

Inwomen, the decline in estrogen levels leads to menopause. Inmen, testosterone levels usually decrease gradually. Decreased levels of growth hormone may lead to decreased muscle mass and strength. Decreased melatonin levels may play an important role in the loss of normal sleep-wake cycles (circadian rhythms) with aging.

Hormones that usually remainunchangedorslightly decreaseinclude the following:

• Cortisol
• Insulin
• Thyroid hormones

Hormones that mayincrease secretionslevels include the following:

Parathyroid hormone

• Follicle-stimulating hormone (FSH)
• Luteinizing hormone (LH)
• Norepinephrine
• Epinephrine, in the very old

Mendel developed theories of genetics that scientists around the world use today.

From experiments with garden peas, Mendel developed a simple set of rules that accurately predicted patterns of heredity. He discovered that plants eitherself-pollinateorcross-pollinate, when the pollen from one plant fertilizes the pistil of another plant. He also discovered that traits are eitherdominantorrecessive. Dominant traits are expressed, and recessive traits are hidden.

Mendel’s Theory of Heredity

To explain his results, Mendel proposed a theory that has become the foundation of the science of genetics. The theory has five elements:

• Parents do not transmit traits directly to their offspring. Rather, they pass on units of information calledgenes.
• For each trait, an individual has two factors: one from each parent. If the two factors have the same information, the individual ishomozygousfor that trait. If the two factors are different, the individual isheterozygousfor that trait. Each copy of a factor, orgene, is called anallele.
• The alleles determine the physical appearance, orphenotype. The set of alleles an individual has is itsgenotype.
• An individual receives one allele from each parent.
• The presence of an allele does not guarantee that the trait will be expressed.

A cell copies its DNA during the S phase, and nucleotides are the building blocks of DNA. Thus, the step preceding the S phase, theG1phase, is the phase of the cell cycle when the cell would contain the most nucleotides.

For a cell to divide into more cells, it must grow, copy its DNA, and produce new daughter cells. Thecell cycleregulates cellular division. This process can either prevent a cell from dividing or trigger it to start dividing.

The cell cycle is an organized process divided into two phases:interphaseand theM (mitotic) phase. During interphase, the cell grows and copies its DNA. After the cell reaches the M phase, division of the two new cells can occur. The G1, S, and G2phases make up interphase.

• G1:The first gap phase, during which the cell prepares to copy its DNA
• S:The synthesis phase, during which DNA is copied
• G2:The second gap phase, during which the cell prepares for cell division

It may appear that little is happening in the cell during the gap phases. Most of the activity occurs at the level of enzymes and macromolecules. The cell produces things like nucleotidesfor synthesizing new DNA strands, enzymes for copying the DNA, and tubulin proteins for building the mitotic spindle. During the S phase, the DNA in the cell doubles, but few other signs are obvious under the microscope. All the dramatic events that can be seen under a microscope occur during the M phase: the chromosomes move, and the cell splits into two new cells with identical nuclei.

In this reaction, chlorine (Cl2) is an element in the reaction that replaces iodine in the compound sodium iodide (NaI). This allows chlorine to form a compound with sodium (NaCl) and leaves iodine (I2) as an element.

Synthesisreactions involve two or more reactants (A and B) combining to form one product (AB). In the example provided, hydrogen (H2) and oxygen (O2) begin as separate elements. At the end of the reaction, the hydrogen and oxygen atoms are bonded in a molecule of water (H2O).

Decompositionreactions have only one reactant (AB) that breaks apart into two or more products (A and B). In the example above, hydrogen peroxide (H2O2) breaks apart into two smaller molecules: water (H2O) and oxygen (O2).

Single-replacementreactions involve two reactants, one compound (AB) and one element (C). In this type of reaction, one element replaces another to form a new compound (AC), leaving one element by itself (B). In the example, zinc replaces hydrogen in hydrochloric acid (HCl). As a result, zinc forms a compound with chlorine, zinc chloride (ZnCl2), and hydrogen (H2) is left by itself.

Double-replacementreactions involve two reactants, both of which are compounds made of two components (AB and CD). In the example, silver nitrate, composed of silver (Ag1+) and nitrate (NO31-) ions, reacts with sodium chloride, composed of sodium (Na1+) and chloride (Cl1-) ions. The nitrate and chloride ions switch places to produce two compounds that are different from those in the reactants.

Combustionreactions occur when fuels burn, and they involve specific reactants and products, as seen in the examples below. Some form of fuel that contains carbon and hydrogen is required. Examples of such fuels are methane, propane in a gas grill, butane in a lighter, and octane in gasoline. Notice that these fuels all react with oxygen, which is necessary for anything to burn. In all combustion reactions, carbon dioxide, water, and energy are produced. When something burns, energy is released, which can be felt as heat and seen as light.

Taxonomy is the process of classifying, describing, and naming organisms. There are seven levels in the Linnaean taxonomic system, starting with the broadest level, kingdom, and ending with the species level. For example, in the image the genus level contains two types of bears, but the species level shows one type. Additionally,organisms in each level are found in the level above it. For example, organisms in the order level are part of the class level. This classification system is based on physical similarities across living things. It does not account for molecular or genetic similarities.

The protein disc that holds two sister chromatids together is what collectively makes a chromosome. A gene is a segment of DNA, deoxyribonucleic acid, which transmits information from parent to offspring. A single molecule of DNA has thousands of genes. A chromosome is a rod-shaped structure that forms when a single DNA molecule and its associated proteins coil tightly before cell division.

Chromosomes have two components:

• Chromatids: two copies of each chromosome
• Centromeres: protein discs that attach the chromatids together

Human cells have 23 sets of different chromosomes. The two copies of each chromosome are called homologous chromosomes, or homologues. An offspring receives one homologue from each parent. When a cell contains two homologues of each chromosome, it is termed diploid (2n). A haploid (n) cell contains only one homologue of each chromosome. The only haploid cells humans have are the sperm and eggs cells known as gametes.

Autotrophs are organisms that use basic raw materials in nature, like the sun, to make energy-rich biomolecules. Minerals are naturally inorganic.

Autotrophsare organisms that make energy-rich biomolecules from raw material in nature. They do this by using basic energy sources such the sun. This explains why most autotrophs rely on photosynthesis to transform sunlight into usable food that can produce energy necessary for life. Plants and certain species of bacteria are autotrophs.

Autotrophs, such as plants, use carbon dioxide (CO2) during photosynthesis to create chemical energy in the form of sugar molecules (like glucose) for growth.

The primary organ of the urinary system is the kidney. Blood from the heart flows through the kidneys via the renal artery. As blood drains from the kidney, it exits through a series of veins, the most prominent of which is the renal vein. When urine is produced, it does not drain through the tubes through which blood flows. Rather, urine flows through two ureters before emptying into the urinary bladder.

The following steps outline how the urinary system works:

• Kidney filters and excretes wastes from blood, producing urine.
• Urine flows down the ureters.
• Urine empties into the bladder and is temporarily stored.
• Bladder, when filled, empties urine out of the body via the urethra.