Which of the following is a component of a chromosome?

A person can be a universal blood donor or acceptor. A universal blood donor has type O blood, while a universal blood acceptor has type AB blood.

There are several different types or groups of blood, andthe major groups are A, B, AB, and O. Blood group is a way to classify blood according to inherited differences of red blood cellantigensfound on the surface of a red blood cell. The type ofantibodyin blood also identifies a particular blood group. Antibodies are proteins found in the plasma. They function as part of the body’s natural defense to recognize foreign substances and alert the immune system.

Depending on which antigen is inherited, parental offspring will have one of the four major blood groups. Collectively, the following major blood groups comprise the ABO system:

• Blood group A: Displays type A antigens on the surface of a red blood cell and contains B antibodies in the plasma.
• Blood group B: Displays type B antigens on the red blood cell’s surface and contains A antibodies in the plasma.
• Blood group O: Does not display A or B antigens on the surface of a red blood cell. Both A and B antibodies are in the plasma.
• Blood group AB: Displays type A and B antigens on the red blood cell’s surface, but neither A nor B antibodies are in the plasma

In addition to antigens, the Rh factor protein may exist on a red blood cell’s surface. Because this protein can be either present (+) or absent (-), it increases the number of major blood groups from four to eight: A+, A-, B+, B-, O+, O-, AB+, and AB-.

Pathogenis an infectious foreign body that enters the body and causes disease or illness to the person. There are five types of pathogens: viruses, bacteria, fungi, protozoa, and worms. Pathogens have antigen proteins found on their surface and are unique to each pathogen.

Antibodyis a protein produced by the body’s immune system when it detects harmful substances (antigens). There are many different antibodies found in the body. Each one is unique and protects the body against the specific antigen that it detects at any given time. If there are no antibodies for a specific antigen, the more likely you are to develop an illness.

Vaccinationsare the introduction of a dead or disabled pathogen or of a harmless microbe with the protein of a pathogen on its surface into the body. Often administered through needle injection, to stimulate the immune system to produce immunity to a specific disease Immunity protects the body from a disease when exposed to it.

There are four types of immunity: natural/passive, natural/active, artificial/passive, and artificial/ active.

• Natural/passive – Babies receive immunities from breastmilk.
• Natural/active – The body produces antibodies to combat an illness when a person becomes sick.
• Artificial/passive – This immunity is temporary and requires doses of serum to maintain the immunity.
• Artificial/active – A vaccination provides artificial/active immunity.

Atissueis a group of cells with similar structure and function and similar extracellular substances located between the cells. The table below describes the four primary tissues found in the human body.

body.

If the cohesion between particles decreases, then the particles must be undergoing a phase change that allows particles to move farther apart. This happens when a substance vaporizes and turns from liquid to gas. Any phase change that moves to the right in the diagram above requires energy to be added to the system because the substance has more energy at the end of the phase change. The phase changes aremelting,vaporization (boiling), andsublimation. When energy is added, particles move faster and can break away from each other more easily as they move to a state of matter with a higher amount of energy. This is most commonly done by heating the substance.

Once the food has been masticated in the oral cavity (mouth), it is then swallowed and travels back into the pharynx down into the esophagus, which leads into the stomach.

Theaging processaffects hormone activity in one of three ways: their secretion can decrease, remain unchanged, or increase.

Hormones thatdecrease secretioninclude the following:

• Estrogen (in women)
• Testosterone (in men)
• Growth hormone
• Melatonin

Inwomen, the decline in estrogen levels leads to menopause. Inmen, testosterone levels usually decrease gradually. Decreased levels of growth hormone may lead to decreased muscle mass and strength. Decreased melatonin levels may play an important role in the loss of normal sleep-wake cycles (circadian rhythms) with aging.

Hormones that usually remainunchangedorslightly decreaseinclude the following:

• Cortisol
• Insulin
• Thyroid hormones

Hormones that mayincrease secretionslevels include the following:

Parathyroid hormone

• Follicle-stimulating hormone (FSH)
• Luteinizing hormone (LH)
• Norepinephrine
• Epinephrine, in the very old

The protein disc that holds two sister chromatids together is what collectively makes a chromosome. A gene is a segment of DNA, deoxyribonucleic acid, which transmits information from parent to offspring. A single molecule of DNA has thousands of genes. A chromosome is a rod-shaped structure that forms when a single DNA molecule and its associated proteins coil tightly before cell division.

Chromosomes have two components:

• Chromatids: two copies of each chromosome
• Centromeres: protein discs that attach the chromatids together

Human cells have 23 sets of different chromosomes. The two copies of each chromosome are called homologous chromosomes, or homologues. An offspring receives one homologue from each parent. When a cell contains two homologues of each chromosome, it is termed diploid (2n). A haploid (n) cell contains only one homologue of each chromosome. The only haploid cells humans have are the sperm and eggs cells known as gametes.

Before mitosis or meiosis occurs, interphase must happen. This is when the cell cycle takes place. The cell cycle is an organized process divided into two phases:interphaseand theM (mitotic) phase. During interphase, the cell grows and copies its DNA. After the cell reaches the M phase, division of the two new cells can occur. The G1, S, and G2phases make up interphase.

Homeostasisis the existence and maintenance of a relatively constant environment within the body. Each cell of the body is surrounded by a small amount of fluid, and the normal functions of each cell depend on the maintenance of its fluid environment within a narrow range of conditions, including temperature, volume, and chemical content. These conditions are known asvariables. For example, body temperature is a variable that can increase in a hot environment or decrease in a cold environment.

There are two types of feedback mechanisms in the human body: negative and positive.

• Negative Feedback: Most systems of the body are regulated by negative feedback mechanisms, which maintain homeostasis. Negative means that any deviation from the set point is made smaller or is resisted. The maintenance of normal blood pressure is a negative-feedback mechanism. Normal blood pressure is important because it is responsible for moving blood from the heart to tissues.
• Positive Feedback: Positive-feedback mechanisms are not homeostatic and are rare in healthy individuals. Positive means that when a deviation from a normal value occurs, the response of the system is to make the deviation even greater. Positive feedback therefore usually creates a cycle leading away from homeostasis and, in some cases, results in death. Inadequate delivery of blood to cardiac muscle is an example of positive feedback.

A cell copies its DNA during the S phase, and nucleotides are the building blocks of DNA. Thus, the step preceding the S phase, theG1phase, is the phase of the cell cycle when the cell would contain the most nucleotides.

For a cell to divide into more cells, it must grow, copy its DNA, and produce new daughter cells. Thecell cycleregulates cellular division. This process can either prevent a cell from dividing or trigger it to start dividing.

The cell cycle is an organized process divided into two phases:interphaseand theM (mitotic) phase. During interphase, the cell grows and copies its DNA. After the cell reaches the M phase, division of the two new cells can occur. The G1, S, and G2phases make up interphase.

• G1:The first gap phase, during which the cell prepares to copy its DNA
• S:The synthesis phase, during which DNA is copied
• G2:The second gap phase, during which the cell prepares for cell division

It may appear that little is happening in the cell during the gap phases. Most of the activity occurs at the level of enzymes and macromolecules. The cell produces things like nucleotidesfor synthesizing new DNA strands, enzymes for copying the DNA, and tubulin proteins for building the mitotic spindle. During the S phase, the DNA in the cell doubles, but few other signs are obvious under the microscope. All the dramatic events that can be seen under a microscope occur during the M phase: the chromosomes move, and the cell splits into two new cells with identical nuclei.