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A 22 kg patient has an ordered for cefazolin 500 mg IV every 6 hours. The safe dose is 50 mg/kg/day. Is the ordered dose safe for the patient?
Answer and Explanation

The Correct Answer is ["1100 mg\/day"," not safe"]

Given:

  • Patient weight = 22 kg
  • Ordered dose = 500 mg IV every 6 hours (4 doses/day)
  • Safe dose = 50 mg/kg/day

Step 1: Calculate the maximum safe daily dose

Maximum safe dose = 50 mg/kg/day × 22 kg

50 × 22 = 1100 mg/day

Step 2: Calculate the ordered daily dose

Ordered dose = 500 mg per dose × 4 doses/day

500 × 4 = 2000 mg/day

Step 3: Compare the ordered dose with the maximum safe dose

  • Maximum safe dose = 1100 mg/day
  • Ordered dose = 2000 mg/day

2000 mg/day > 1100 mg/day → not safe


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Related Questions

Correct Answer is C

Explanation

A. This is incorrect because Rho(D) immune globulin is not given only after delivery. It is routinely administered during pregnancy to prevent Rh sensitization that can occur from fetal–maternal blood mixing before birth.
B. This is incorrect because Rho(D) immune globulin is not given monthly. Routine administration occurs once at approximately 28 weeks of gestation and again postpartum if the newborn is Rh-positive.
C. This is correct because an Rh-negative, unsensitized pregnant woman should receive Rho(D) immune globulin at 28 weeks of gestation and within 72 hours after delivery if the infant is Rh-positive. This prevents the mother from forming antibodies against Rh-positive red blood cells.
D. This is incorrect because Rho(D) immune globulin is needed during the first pregnancy and any subsequent pregnancies if the mother is Rh-negative and unsensitized. Sensitization can occur during any pregnancy, not just after the second.

Correct Answer is ["0.11"]

Explanation

Given:

  • Patient weight = 5.6 kg
  • Digoxin safe dose = 0.03–0.06 mg/kg/day

Step 1: Calculate the maximum daily dose
Maximum dose = 0.06 mg/kg/day × 5.6 kg

0.06 × 5.6 = 0.336 mg/day

Step 2: Round to the nearest hundredth
0.336 → 0.34 mg/day

Step 3: Divide by the number of doses per day (every 8 hours → 3 times/day)
Maximum single dose = 0.34 mg ÷ 3

0.34 ÷ 3 ≈ 0.1133 mg

Rounded to the nearest hundredth → 0.11 mg per dose

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