A 3-year-old child with a history of recurrent respiratory infections, poor weight gain, and salty-tasting skin is being evaluated for cystic fibrosis (CF). The healthcare provider suspects CF and orders a diagnostic test. Which of the following diagnostic tests is the gold standard for confirming the diagnosis of CF?
Genetic testing for CFTR mutations
Sweat chloride test
Chest x-ray
Pulmonary function tests (PFTS)
The Correct Answer is B
A. Genetic testing for CFTR mutations is incorrect as the primary diagnostic tool. While genetic testing can identify specific CF mutations and is useful for screening or confirming atypical cases, it is not considered the first-line gold standard for diagnosis.
B. Sweat chloride test is correct. The sweat chloride test measures the concentration of chloride in sweat, which is abnormally elevated in individuals with cystic fibrosis due to defective CFTR channels. A chloride concentration ≥60 mmol/L on two separate occasions confirms the diagnosis. It remains the gold standard diagnostic test for CF in children.
C. Chest x-ray is incorrect because it is not diagnostic for CF. Although chest x-rays may show structural lung changes such as hyperinflation or bronchiectasis in advanced disease, they cannot confirm CF on their own.
D. Pulmonary function tests (PFTs) are incorrect for initial diagnosis in young children. PFTs assess lung function and disease progression but are not reliable for confirming CF, especially in a 3-year-old who may not be able to perform the maneuvers required.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Directional trends describe the general patterns of growth, such as cephalocaudal (head-to-toe) or proximodistal (center-to-periphery) development. The scenario focuses on differences in the rate of skill acquisition, not the direction of development.
B. Developmental pace refers to the rate at which different skills or abilities emerge, which can vary among domains. In this scenario, the toddler’s language skills are advancing rapidly, while gross motor skills like running show little change, illustrating that different areas of development progress at different rates.
C. Sensitive periods refer to specific windows of time during which a child is particularly responsive to certain types of learning or stimuli, such as language acquisition. The scenario does not specify a critical timing for development, but rather differences in progression across skills, so sensitive periods are not the primary principle illustrated.
D. Sequential trends refer to the orderly and predictable progression of developmental milestones, such as crawling before walking. While the toddler is developing language, the scenario emphasizes rate differences, not the order in which skills emerge.
Correct Answer is ["B","D","E"]
Explanation
A. This is incorrect. There is no safe level of illicit opioid use during pregnancy. Encouraging or implying safety could put both the mother and fetus at serious risk, including preterm labor, low birth weight, and neonatal abstinence syndrome (NAS).
B. Providing a supportive, nonjudgmental approach encourages the client to engage in care, disclose substance use, and access rehabilitation, counseling, and social services, which improves maternal and fetal outcomes.
C. Abrupt cessation of opioids in a dependent pregnant client can lead to maternal withdrawal, fetal distress, preterm labor, or miscarriage. Safe management involves medically supervised opioid replacement therapy, not sudden discontinuation.
D. Infants exposed to opioids in utero are at risk for NAS, which includes tremors, irritability, feeding difficulties, respiratory problems, and seizures. Early identification and intervention are essential.
E. Methadone or buprenorphine therapy is the standard of care for managing opioid dependence during pregnancy. These therapies stabilize maternal opioid levels, reduce illicit drug use, and improve pregnancy outcomes. Therapy should be medically supervised.
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