A 6-year-old child is prescribed tetracycline for a severe infection. Which adverse effect should the nurse monitor for during therapy?
Ototoxicity
Tooth discoloration
Nephrotoxicity
Hyperglycemia
The Correct Answer is B
A. Ototoxicity.: Ototoxicity is more commonly associated with aminoglycosides such as gentamicin or vancomycin, not tetracyclines. These drugs can damage the auditory nerve, but tetracyclines do not affect hearing or balance mechanisms in the inner ear.
B. Tooth discoloration.: Tetracyclines can bind to calcium in developing teeth and bones, causing permanent yellow-gray or brown discoloration. This effect is especially concerning in children under 8 years old, whose teeth and bones are still forming, making the drug contraindicated for pediatric use unless absolutely necessary.
C. Nephrotoxicity.: Nephrotoxicity (kidney damage) can occur, especially with outdated tetracycline preparations or in patients with pre-existing renal issues, but it is not the primary reason for the drug's contraindication in children under 8 years old.
D. Hyperglycemia.: Tetracyclines have no known effect on blood glucose regulation. Hyperglycemia may occur with corticosteroids or certain antipsychotics but is not a recognized adverse reaction associated with tetracycline therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Impotence.: Cimetidine, an H2 receptor antagonist, can cause endocrine-related adverse effects such as impotence, decreased libido, and gynecomastia in men. Cimetidine can block androgen receptors and increase prolactin levels, altering normal hormonal balance.
B. Hair growth.: Cimetidine does not promote hair growth. Excessive hair growth (hirsutism) is unrelated to H2 blockers and is more commonly associated with hormonal imbalances or specific endocrine disorders rather than this medication.
C. Priapism.: Prolonged, painful erection (priapism) is not a known side effect of cimetidine. It is more often associated with certain psychiatric medications or erectile dysfunction drugs that affect vascular blood flow.
D. Hypersecretion of stomach acid.: Cimetidine decreases, not increases, gastric acid production by blocking histamine receptors in the stomach lining. It is used to treat peptic ulcer disease, GERD, and gastritis by reducing acid secretion and promoting mucosal healing.
Correct Answer is C
Explanation
A. Administer the drug as an IV piggyback with another drug.: Amphotericin B should never be mixed or administered with other medications in the same IV line because it is incompatible with many drugs. Doing so could lead to precipitation or reduced drug potency.
B. Check the client's serum calcium levels.: While electrolyte monitoring is important during therapy, amphotericin B primarily causes hypokalemia and hypomagnesemia rather than significant calcium changes. Checking calcium is not the immediate priority.
C. Administer a test dose of 1 mg, over 30 minutes.: Amphotericin B is highly nephrotoxic and can cause severe hypersensitivity reactions such as fever, chills, hypotension, or anaphylaxis. Administering a small test dose first allows the nurse to assess the client’s tolerance and detect potential adverse reactions before giving the full therapeutic dose.
D. Administer an absorbate antidiarrheal medication 30 minutes prior to administration.: Amphotericin B is not associated with diarrhea as a major side effect. The focus should instead be on test dosing, prehydration, and monitoring for infusion reactions.
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