The nurse knows that the antibiotic, piperacillin/tazobactam (Zosyn), can best be described as a

It is a natural penicillin indicated for Gram + organisms only

It is a narrow spectrum macrolide antibiotic

It is broad-spectrum penicillin combined with a beta-lactamase inhibitor

It is an anti-fungal medication

Answer and Explanation

The Correct Answer is C

A. It is a natural penicillin indicated for Gram + organisms only.: Natural penicillins, such as penicillin G and V, are mainly effective against Gram-positive bacteria but have limited activity against Gram-negative organisms. Piperacillin/tazobactam, however, is a synthetic extended-spectrum penicillin with coverage beyond Gram-positive bacteria.

B. It is a narrow spectrum macrolide antibiotic.: Piperacillin/tazobactam is not a macrolide; macrolides such as erythromycin and azithromycin act by inhibiting bacterial protein synthesis. Zosyn instead works by disrupting bacterial cell wall formation and inhibiting beta-lactamase enzymes.

C. It is broad-spectrum penicillin combined with a beta-lactamase inhibitor.: Piperacillin provides extended-spectrum coverage against both Gram-positive and Gram-negative organisms, including Pseudomonas species. The addition of tazobactam, a beta-lactamase inhibitor, prevents enzymatic breakdown of piperacillin, enhancing its effectiveness.

D. It is an anti-fungal medication.: Piperacillin/tazobactam has no antifungal properties. Antifungal drugs, such as fluconazole or amphotericin B, are used to treat fungal infections, whereas Zosyn specifically targets bacterial pathogens.

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Correct Answer is A

Explanation

A. Reduction in frequency of COPD exacerbations: The combination of a long-acting beta2-agonist and an inhaled corticosteroid helps relax airway smooth muscles and reduce airway inflammation. This dual action improves airflow, decreases symptoms such as dyspnea, and lowers the risk and frequency of COPD exacerbations, enhancing disease management.

B. Exacerbation of inflammation and bronchoconstriction: Inhaled corticosteroids and LABAs work to decrease inflammation and promote bronchodilation. They do not worsen airway inflammation or constriction; rather, they improve respiratory function and symptom control.

C. Cure of underlying COPD pathology: COPD is a chronic, progressive disease with irreversible structural changes in the lungs. Medications like LABA/ICS improve symptoms and reduce exacerbations but do not cure the underlying pathology.

D. Prevention of pneumonia: While inhaled corticosteroids may slightly increase the risk of pneumonia in some COPD patients, the combination therapy is not intended to prevent infections. Its primary goal is symptom control and reduction of exacerbations.

A. Scopolamine B. Metoclopramide C. Methylcellulose D. Ondanestron

Correct Answer is D

Explanation

A. Scopolamine.: Scopolamine is an anticholinergic primarily used to prevent motion sickness or postoperative nausea related to anesthesia. It is not the preferred agent for chemotherapy-induced nausea and vomiting because it does not target serotonin receptors involved in chemotherapy-related emesis.

B. Metoclopramide.: Metoclopramide is a prokinetic and antiemetic that enhances gastric motility and is sometimes used for mild to moderate nausea. However, it is less effective against the severe nausea caused by chemotherapy and may cause extrapyramidal side effects

C. Methylcellulose.: Methylcellulose is a bulk-forming laxative used to treat constipation by increasing stool volume and water content. It has no antiemetic properties and would not be useful in preventing chemotherapy-related nausea or vomiting.

D. Ondansetron.: Ondansetron is a serotonin 5-HT3 receptor antagonist that effectively prevents chemotherapy-induced nausea and vomiting. Administering it 30–60 minutes before treatment blocks serotonin release from the gastrointestinal tract, reducing nausea severity.

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The nurse knows that the antibiotic, piperacillin/tazobactam (Zosyn), can best be described as a

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for a patient with chronic obstructive pulmonary disease (COPD) who has been prescribed a combination inhaler containing a long acting beta2-agonist (LABA) and an inhaled corticosteroid (ICS). Which therapeutic effect should the nurse expect from this medication?

Correct Answer is A

Explanation

A client with a diagnosis of cancer is scheduled for chemotherapy. The nurse anticipates administering which of the following medications, 30-60 minutes prior to chemotherapy treatment?

Correct Answer is D

Explanation

A nurse is preparing to administer pantoprazole (Protonix) to a client diagnosed with GERD. To ensure maximum therapeutic effect, the nurse should teach the client that this medication works best when administered:

A client with primary open-angle glaucoma is prescribed latanoprost 0.005% ophthalmic solution. Which instructions should the nurse give to the client to maximize efficacy and minimize adverse effects?

A patient is scheduled to have a pacemaker implanted at 0800 in the cardiac cath lab. The night shift nurse has an order to draw labs, check the patient's vital signs, and start antibiotics prior to the day shift arriving. The nurse understands that the antibiotics are intended to?

A client with AIDS has an order to start Amphotericin B. Which intervention should the nurse implement first?

A patient with a history of vancomycin-resistant Enterococcus (VRE) infection is prescribed vancomycin. Which of the following actions should the nurse take first?

A client with GERD has been taking omeprazole 40 mg daily for 18 months. The nurse knows that what potential adverse effect is the client as risk for?

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The nurse knows that which of the following interventions are appropriate steps in the administration of ear drops to a child under three years of age?