A child with spastic cerebral palsy is to receive botulin toxin.
The nurse prepares the child for administration of this drug by which route?
Oral.
Subcutaneous injection.
Intramuscular injection.
Intravenous infusion.
The Correct Answer is C
Choice A rationale
Oral administration of botulinum toxin is not effective for treating spasticity in cerebral palsy. The toxin, a neurotoxin that blocks acetylcholine release at the neuromuscular junction, would be rapidly inactivated by gastric acid and digestive enzymes in the gastrointestinal tract, preventing it from reaching the targeted spastic muscles.
Choice B rationale
Subcutaneous injection of botulinum toxin is not the correct route for treating focal spasticity. This route targets the layer beneath the skin and is often used for systemic absorption, but it does not adequately deliver the drug directly into the bulk of the affected, spastic muscles to achieve localized chemodenervation.
Choice C rationale
Botulinum toxin is administered via intramuscular injection directly into the specific muscles identified as being hypertonic or spastic. This localized injection allows the toxin to block the release of acetylcholine at the presynaptic terminals of the neuromuscular junction, thereby temporarily paralyzing or relaxing the targeted muscles for several months.
Choice D rationale
Intravenous infusion of botulinum toxin is not used for treating spasticity because this route would lead to systemic distribution. This would result in widespread muscle weakness or paralysis, which is an undesirable and potentially dangerous side effect, rather than the intended localized reduction in focal spasticity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale
Astigmatism is an irregular curvature of the cornea or lens, which causes light rays to focus unevenly on the retina, resulting in distorted or blurred vision at any distance. The primary treatment for astigmatism is the use of corrective lenses, such as eyeglasses or contact lenses, not therapeutic eye patching.
Choice B rationale
Hyperopia, or farsightedness, occurs when the light focuses behind the retina because the eyeball is too short or the cornea is too flat, causing difficulty seeing objects up close. This condition is primarily managed by prescribing convex corrective lenses to help shift the focal point onto the retina.
Choice C rationale
Myopia, or nearsightedness, occurs when the light focuses in front of the retina because the eyeball is too long or the cornea is too steep, causing blurry distance vision. The standard treatment involves concave corrective lenses to diverge light rays and properly position the focal point on the retina.
Choice D rationale
Amblyopia, commonly called "lazy eye," is a reduction in visual acuity in one eye that results from the eye and brain not working well together, often caused by untreated strabismus or refractive errors. Patching the strong eye forces the brain to use the weaker, amblyopic eye, stimulating the development of the neural pathways necessary for clear vision.
Correct Answer is C
Explanation
Choice A rationale
The normal range for meconium passage is generally within the first 24 to 48 hours of life. A 16-hour-old newborn who has not yet passed any meconium is still within the expected time frame and is not an immediate cause for alarm, although documentation is important. However, the nurse should continue to monitor for bowel sounds and abdominal distention.
Choice B rationale
The normal blood glucose level for a newborn is typically 45 mg/dL or higher. A glucose level of 55 mg/dL for a 16-hour-old newborn is within the acceptable and safe range, indicating adequate metabolic function and requiring only routine monitoring rather than immediate reporting to the healthcare provider.
Choice C rationale
A respiratory rate of 70 breaths/minute in a 2-day-old newborn (48 hours old) is tachypnea, as the normal range is 30 to 60 breaths/minute. Persistent tachypnea beyond the immediate transitional period, especially when associated with an irregular pattern, is a sign of potential respiratory distress or other underlying pulmonary or cardiac pathology and must be reported immediately.
Choice D rationale
Excreting a milky discharge (sometimes called "witch's milk") from the nipples in both female and male newborns is a common and benign temporary condition caused by the withdrawal of maternal hormones (estrogen and prolactin) after birth. This is a normal, transient finding and does not require reporting to the healthcare provider.
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