A client with hemophilia A asks the nurse about the cause of the condition.
Which response by the nurse is accurate?

Choice A rationale:

The client has a normal coagulation profile.

This choice is incorrect because the client's prolonged PTT suggests a problem with the intrinsic pathway of coagulation, which is typical in hemophilia.

A normal coagulation profile would show normal values for both PTT and PT.

Choice B rationale:

The client may have a vitamin K deficiency.

This choice is not applicable in this context.

A vitamin K deficiency primarily affects the extrinsic pathway of coagulation, leading to an elevated PT, but it does not typically affect the PTT, which is prolonged in hemophilia.

Choice C rationale:

The client likely has hemophilia.

This is the correct choice.

Hemophilia is characterized by a deficiency or dysfunction of clotting factors, most commonly factor VIII (hemophilia A) or factor IX (hemophilia B)

Prolonged PTT with normal PT is a classic laboratory finding in hemophilia.

Choice D rationale:

The client is at risk for thrombosis.

This choice is incorrect.

Hemophilia is associated with bleeding tendencies, not an increased risk of thrombosis.

Prolonged PTT indicates a reduced ability to form clots, making thrombosis less likely.

Choice A rationale:

Hemophilia A and hemophilia B are both types of hemophilia, but hemophilia A is actually less common than hemophilia B.

The prevalence of hemophilia A is about 1 in 5,000 males, whereas hemophilia B occurs in about 1 in 25,000 males.

Therefore, this statement is incorrect.

Choice B rationale:

Hemophilia is not inherited through a defective gene on the Y chromosome.

Hemophilia is an X-linked recessive genetic disorder, which means it is caused by a mutation in genes located on the X chromosome, not the Y chromosome.

This statement is incorrect.

Choice C rationale:

This statement is correct.

Males inherit hemophilia from their mothers who carry the defective gene on one of their X chromosomes.

However, it's important to note that females can also be carriers of the gene and can pass it on to their sons.

This statement does not indicate a need for further teaching.

Choice D rationale:

This statement is incorrect.

While it is very rare for females to have hemophilia, it is not impossible.

Females can inherit hemophilia if they have two affected X chromosomes or if they inherit one affected X chromosome and one affected Y chromosome.

Therefore, this statement does not indicate a need for further teaching.