A nurse is preparing to administer phenytoin IV to a client who had a tonic-clonic seizure. Which of the following actions should the nurse plan to take?
Inject sterile water after administration.
Administer the medication with 5% dextrose in water.
Discard the medication if it appears cloudy.
Administer the medication at a rate of 100 mg/min.
The Correct Answer is C
Phenytoin is a potent antiepileptic that requires extreme caution during intravenous administration due to its high alkalinity and potential for precipitation. It is incompatible with most intravenous solutions and must be delivered through a large-bore catheter to prevent extravasation and tissue necrosis. Close cardiovascular monitoring is mandatory during infusion to detect potential arrhythmias or severe hypotension.
Rationale:
A. Injecting sterile water after administration is not the standard protocol; instead, the line must be flushed with 0.9% sodium chloride. Phenytoin is highly unstable and will precipitate if it comes into contact with many other fluids. Using 0.9% sodium chloride ensures the vein is cleared of the medication without causing the formation of dangerous micro-crystals in the IV tubing.
B. Administering phenytoin with 5% dextrose in water (D5W) is strictly contraindicated because the medication will immediately precipitate into a solid form. Phenytoin is only compatible with 0.9% sodium chloride, and any contact with glucose-containing solutions leads to crystallization. Such precipitates can cause emboli or severe vein irritation, compromising the safety of the intravenous access site.
C. Discarding the medication if it appears cloudy is a critical safety action because cloudiness indicates that the phenytoin has precipitated. Intravenous phenytoin should be a clear, colorless solution; any presence of crystals or opaqueness means the drug is no longer safe for infusion. Injecting a precipitated solution can cause catastrophic vascular damage or pulmonary embolism in the client.
D. Administering the medication at a rate of 100 mg/min is dangerously fast and exceeds the maximum recommended safety limit. To prevent severe hypotension and cardiac arrhythmias, the infusion rate must not exceed 50 mg/min for adults. Rapid administration can lead to cardiovascular collapse, making slow, controlled delivery and continuous heart rate monitoring an essential nursing priority.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Sodium polystyrene sulfonate is a cation-exchange resinutilized in the management of hyperkalemia. It works in the large intestine by exchanging sodium ions for potassium ions, allowing the excess potassiumto be excreted from the body via the feces to prevent cardiac complications.
Rationale:
A.While sodium polystyrene sulfonate can lead to a secondary decrease in calcium levels as a side effect, calcium is not the target of the medication. Monitoring calcium is important for safety, but it does not measure the primary effectiveness of the drug. The drug is specifically formulated to treat potassium imbalances that pose immediate risks to the myocardium.
B.Potassium is the primary laboratory value to monitor because the therapeutic goal of sodium polystyrene sulfonate is to lower serum potassium levels. Effectiveness is confirmed when the lab results show a return toward the normal range of 3.5 to 5.0 mEq/L. Since high potassium can cause fatal arrhythmias, this lab provides the definitive proof of the medication's clinical success.
C.Sodium levels may increase during therapy because the resin releases sodium in exchange for potassium, but this is a side effect rather than a measure of efficacy. Monitoring sodium is necessary to prevent hypernatremia and fluid retention, especially in heart failure patients. However, the nurse prioritizes the potassium level to ensure the life-threatening hyperkalemia has been resolved.
D.Magnesium levels are not the primary focus for evaluating the effectiveness of this exchange resin. While electrolyte shifts can occur broadly during diuresis or bowel clear-out, sodium polystyrene sulfonate has a specific affinity for potassium. The nurse should monitor magnesium for general electrolyte balance, but it does not serve as a benchmark for the medication's intended therapeutic action.
Correct Answer is A
Explanation
The pharmacological management of acute maniainvolves mood stabilizers and antipsychotics to achieve rapid symptomatic control. Safety standards prohibit the use of trailing zerosin medication orders to prevent ten-fold dosing errors. A decimal point followed by a zero can be easily misread in a clinical environment, leading to iatrogenic harmand severe medication toxicity.
Rationale:
A.Risperidone 3.0 mg contains a trailing zero, which is a dangerous notation that must be clarified and corrected to 3 mg. If the decimal point is not clearly visible, a clinician might mistakenly administer 30 mg, which could lead to severe extrapyramidal symptoms or neuroleptic malignant syndrome. Following the "Do Not Use" list from The Joint Commission is essential for patient safety.
B.Clonazepam 0.5 mg is a correctly formatted prescription for a benzodiazepine often used as an adjunct in mania to promote sedation and reduce agitation. The leading zero before the decimal point is required to prevent the dose from being read as 5 mg. Since this order follows safe labeling practices and falls within therapeutic ranges, it does not require clarification.
C.Lithium 300 mg is a standard starting dose for a primary mood stabilizer used in the treatment of bipolar disorder. The order is written clearly without dangerous abbreviations or incorrect decimal placements. Because the dose is typical for achieving a therapeutic serum concentration between 0.8 and 1.2 mEq/L, the nurse can proceed with administration and monitoring.
D.Divalproex sodium 0.5 g is an anticonvulsant mood stabilizer written using a leading zero, which is the correct safety format for decimal values. While often prescribed in milligrams (500 mg), the use of grams is clear and follows standard metric notation. There is no ambiguity in this order that would increase the risk of a significant medication error for the patient.
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