A nurse is preparing to administer venlafaxine 75 mg/day in two divided doses to a client who has depression. Available are 37.5 mg tablets. How many tablets should the nurse administer with each dose?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

To determine how many capsules of rifampin the nurse should administer per dose, we can follow these steps:

Convert the client's weight from pounds to kilograms:

132 lb ÷ 2.2 = 59.9 kg (rounded to one decimal place)

Calculate the total daily dose of rifampin:

20 mg/kg/day × 59.9 kg = 1198 mg/day

Divide the total daily dose into two equal doses for administration:

1198 mg/day ÷ 2 = 599 mg per dose

Calculate the number of capsules needed per dose:

150 mg per capsule

599 mg per dose ÷ 150 mg per capsule = 3.9933...

Rounding to the nearest whole number, the nurse should administer 4 capsules per dose.

Therefore, the nurse should administer 4 capsules of rifampin per dose.

Choice A reason: Age is a non-modifiable risk factor for hypertension because the risk of high blood pressure increases as we get older. This is due to changes in the heart and blood vessels, such as loss of elasticity and stiffening of the arteries, that affect the blood flow and pressure. ¹

Choice B reason: Genetics is a non-modifiable risk factor for hypertension because some people inherit genes that make them more likely to develop high blood pressure. For example, people of African and Black Caribbean descent have a higher risk of hypertension due to genetic variations that affect salt sensitivity and blood vessel function. ²

Choice C reason: Smoking is a modifiable risk factor for hypertension because it can be changed or avoided by quitting tobacco use. Smoking damages the blood vessels and increases the risk of atherosclerosis, which is the buildup of plaque in the arteries that narrows them and raises blood pressure. Smoking also lowers the level of good cholesterol (HDL) and raises the level of bad cholesterol (LDL) and triglycerides, which are fats in the blood that contribute to plaque formation. ³

Choice D reason: Obesity is a modifiable risk factor for hypertension because it can be changed or prevented by losing weight or maintaining a healthy weight. Obesity increases the risk of high blood pressure by putting extra strain on the heart and blood vessels, as well as by causing hormonal and metabolic changes that affect blood pressure regulation. Obesity is also associated with other conditions that can raise blood pressure, such as diabetes, sleep apnea, and kidney disease. ⁴

Choice E reason: Sedentary lifestyle is a modifiable risk factor for hypertension because it can be changed or improved by increasing physical activity. Sedentary lifestyle increases the risk of high blood pressure by reducing the ability of the blood vessels to dilate and contract, as well as by increasing the risk of obesity, diabetes, and high cholesterol. Physical activity helps to lower blood pressure by improving blood flow, strengthening the heart muscle, and lowering body weight and stress levels. .