A patient has an order for Zithromax 1g PO stat.

The Zithromax bottle concentration is 200 mg per 5 mL.

How many mL will you give?

Round to the nearest whole number.

A. Instill one drop in each eye every evening.: Latanoprost is a prostaglandin analog that lowers intraocular pressure by increasing aqueous humor outflow. Administering it once daily in the evening maximizes its efficacy and aligns with the drug’s pharmacokinetics.

B. Instill one drop in each eye only when experiencing visual disturbances.: Latanoprost must be used consistently to maintain controlled intraocular pressure. Intermittent or symptom-based dosing does not prevent the progressive optic nerve damage associated with glaucoma.

C. Instill one drop in each eye every morning.: Morning administration is less effective than evening dosing, as intraocular pressure reduction is greater when latanoprost is applied at night. Evening use also decreases the likelihood of systemic absorption and side effects.

D. Instill one drop in each eye every 12 hours.: Twice-daily dosing is unnecessary and may increase the risk of local adverse effects, such as conjunctival hyperemia, eye irritation, and eyelash changes, without providing additional benefit compared to once-daily evening dosing.

A. Exostosis, or bone overgrowth.: Omeprazole, a proton pump inhibitor (PPI), does not cause bone overgrowth or exostosis. This condition is typically associated with chronic irritation or mechanical stress rather than medication use.

B. Drug induced ototoxicity.: Ototoxicity is linked to medications such as aminoglycoside antibiotics, loop diuretics, and certain chemotherapeutic agents. Omeprazole does not affect the auditory system or cause hearing loss.

C. Osteoporosis-related fracture risk.: Long-term PPI use, such as omeprazole for more than a year, can decrease calcium absorption by reducing gastric acid secretion. This may lead to decreased bone mineral density, increasing the risk for osteoporosis and fractures, particularly of the hip, wrist, and spine.

D. Diminished visual acuity.: Omeprazole is not associated with visual changes or ocular toxicity. Any vision changes would more likely stem from other systemic conditions such as diabetes or hypertension rather than prolonged PPI therapy.