A patient is prescribed carbidopa/levodopa for the treatment of Parkinson's disease. The patient asks the nurse whether this medication will cure their condition.
Which is a correct statement about the effects of carbidopa/levodopa?
It does not alter the underlying disease process, but it may improve a client's quality of life.
It will send the disease into remission and eventually cure the disease.
It will control the symptoms for 10 to 12 years.
It is the treatment of last resort and may control symptoms.
The Correct Answer is A
Choice A rationale
Carbidopa/levodopa functions by supplementing dopamine levels in the brain, alleviating motor symptoms. However, it does not stop the progressive neurodegeneration characteristic of Parkinson's disease, which involves the loss of dopaminergic neurons. While symptoms are managed, the underlying pathology continues, hence it improves quality of life but is not curative.
Choice B rationale
Carbidopa/levodopa provides symptomatic relief by increasing dopamine availability in the brain, addressing the motor deficits of Parkinson's disease. However, it does not halt the ongoing degeneration of dopaminergic neurons in the substantia nigra. Therefore, it cannot induce remission or cure the disease, which is a chronic, progressive neurological disorder.
Choice C rationale
The efficacy of carbidopa/levodopa in controlling Parkinson's symptoms varies significantly among individuals and over time. Its effectiveness typically diminishes after 5-10 years due to disease progression and the development of motor complications, such as dyskinesia and "wearing-off" phenomena. Predicting a precise duration of control like 10-12 years is not scientifically accurate.
Choice D rationale
Carbidopa/levodopa is often considered a cornerstone of Parkinson's disease treatment, particularly for motor symptoms, and is typically initiated when symptoms significantly impact quality of life. It is not generally reserved as a "treatment of last resort" but rather as a primary therapeutic agent, indicating its broad utility and relatively early introduction in management.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Topical corticosteroids are the mainstay of treatment for contact dermatitis. This inflammatory skin condition is characterized by a delayed hypersensitivity reaction, and corticosteroids reduce inflammation, pruritus, and erythema by suppressing the immune response, inhibiting cytokine release, and stabilizing lysosomal membranes, thus alleviating symptoms locally.
Choice B rationale
Intravenous corticosteroids are generally reserved for severe, widespread, or recalcitrant cases of contact dermatitis, or when there is significant systemic involvement, such as severe angioedema or airway compromise. For typical localized contact dermatitis, topical application is preferred to minimize systemic side effects.
Choice C rationale
Intravenous antibiotics are indicated for bacterial infections. Contact dermatitis is an inflammatory, non-infectious condition caused by exposure to an allergen or irritant. Therefore, antibiotics would not be a primary treatment unless there is a secondary bacterial infection complicating the dermatitis, which is not the typical initial presentation.
Choice D rationale
Oral antibiotics, like intravenous antibiotics, are used to treat bacterial infections. Contact dermatitis is not caused by bacteria but rather by an inflammatory immune response to external agents. Administering oral antibiotics without evidence of secondary bacterial infection would be inappropriate and ineffective for treating the underlying dermatitis.
Correct Answer is B
Explanation
Choice A rationale
Collecting the second voided specimen of the day is not the standard procedure for a clean-catch urine sample. A clean-catch specimen aims to collect urine mid-stream after initial flushing, regardless of the time of day, to minimize contamination from the urethra and external genitalia.
Choice B rationale
When obtaining a clean-catch urine specimen, the patient should void a small initial amount into the toilet. This initial stream helps to flush out microorganisms from the distal urethra and periurethral area, reducing contamination of the collected specimen and ensuring a more accurate representation of bladder urine.
Choice C rationale
Restricting fluids before specimen collection is generally contraindicated for a clean-catch urine. Adequate hydration ensures sufficient urine volume for collection and can help to dilute contaminants, making it easier to obtain a clean mid-stream sample. Fluid restriction may lead to a concentrated, insufficient sample.
Choice D rationale
Placing the specimen in a clean urinalysis container is insufficient; the container must be sterile. A non-sterile container can introduce external contaminants into the urine sample, leading to inaccurate laboratory results, potentially causing misdiagnosis or inappropriate treatment for a urinary tract infection.
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