A patient with lung cancer is being treated with chemotherapy and radiation. Which lab values will the nurse monitor to detect bone marrow suppression? Select all that apply.
Platelet count
Red blood cell (RBC) count
Basophil count
Neutrophil count
Correct Answer : A,B,D
A. Platelet count: Chemotherapy and radiation commonly suppress megakaryocyte production in the bone marrow, leading to thrombocytopenia. A decreased platelet count increases the risk of spontaneous bleeding and impaired clot formation. Monitoring platelet levels allows early detection of marrow suppression and guides precautions or interventions.
B. Red blood cell (RBC) count: Myelosuppressive therapy can reduce erythropoiesis, resulting in anemia. A declining RBC count may lead to fatigue, dyspnea, and reduced oxygen-carrying capacity. Serial monitoring helps assess the severity of marrow suppression and determine the need for interventions such as erythropoiesis-stimulating agents or transfusion.
C. Basophil count: Basophils represent a very small fraction of circulating leukocytes and are not used as a primary indicator of bone marrow suppression. While they originate from the marrow, changes in basophil count are neither sensitive nor specific markers of chemotherapy-induced myelosuppression. Other white blood cell parameters provide more clinically meaningful data.
D. Neutrophil count: Neutropenia is a major and potentially life-threatening consequence of bone marrow suppression, significantly increasing the risk of infection. The absolute neutrophil count (ANC) is especially important in oncology patients to guide infection precautions and determine chemotherapy dosing adjustments. Monitoring neutrophils is critical for early identification of immunosuppression.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Confirm that the patient's consent form is signed and in the chart: Ensuring informed consent is critical for legal and ethical reasons, but it does not directly prevent immediate life-threatening complications during transport of an intubated patient.
B. Notify the surgical team of the patient's arrival time: Communicating with the surgical team is important for workflow and preparedness, but it does not directly safeguard the patient’s airway or oxygenation during transport.
C. Document the time the patient left the unit and who accompanied them: Accurate documentation is essential for accountability and continuity of care, yet it does not actively prevent physiologic compromise during transport.
D. Ensure that portable oxygen and suction equipment are functioning and available: Maintaining a patent airway and adequate oxygenation is the highest priority for an intubated patient. Portable oxygen and suction are critical in case of accidental extubation, obstruction, or respiratory compromise during transport, making this the most important safety measure
Correct Answer is B
Explanation
A. BP 102/56 mm Hg: This blood pressure is slightly low but may still be sufficient to maintain perfusion in some patients. Early compensatory mechanisms in shock can maintain perfusion despite borderline hypotension, so while it warrants monitoring, it is not the most critical finding.
B. Urine output 15 ml for 2 hours: Oliguria is a sensitive early indicator of inadequate tissue perfusion in shock. A urine output of less than 0.5 mL/kg/hr reflects decreased renal perfusion and potential impending acute kidney injury, making this the most urgent finding requiring immediate assessment and intervention.
C. Arterial oxygen saturation 92%: Oxygen saturation of 92% is mildly reduced and may indicate early hypoxemia. While concerning, it is less immediately critical than evidence of end-organ hypoperfusion, such as severely reduced urine output.
D. Apical pulse 110 beats/min: Tachycardia is a compensatory response in shock to maintain cardiac output. While it signals stress on the cardiovascular system, it is expected in early shock and is less immediately dangerous than oliguria indicating organ hypoperfusion.
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