A transplant recipient is more likely to reject a transplanted organ if there is not a close match between what of the recipient and that of the donor?
major histocompatibility complex
antibody response
blood type
sex and age
The Correct Answer is A
A. major histocompatibility complex: MHC (human leukocyte antigen, HLA) matching is critical because disparities trigger strong T-cell–mediated rejection responses.
B. antibody response: the recipient’s antibody response intensity matters clinically, but you don’t “match” antibody responses between donor and recipient; rather you try to match MHC and blood type.
C. blood type: blood type mismatches can cause hyperacute rejection and are important to consider, but MHC/HLA matching is the key determinant of long-term rejection risk.
D. sex and age: sex and age are not major determinants of graft compatibility; they are not the primary matching criteria used to reduce rejection risk.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Precipitation: precipitation refers to antigen–antibody complexes forming an insoluble precipitate from soluble antigens, not clumping of whole cells.
B. Agglutination: agglutination is the clumping of cells (like RBCs) when antibodies bind surface antigens, which is what happens in an incompatible transfusion.
C. Chemotaxis: chemotaxis is directed movement of leukocytes toward chemical signals, not antibody-mediated clumping.
D. Opsonization: opsonization is coating a pathogen or cell with molecules (e.g., antibodies, complement) to enhance phagocytosis, not the visible clumping seen in agglutination.
Correct Answer is D
Explanation
A. Maintaining blood glucose concentration: Incorrect (this is a liver function) -the liver stores glycogen and performs gluconeogenesis to regulate blood glucose.
B. Secretion of bile: Incorrect (this is a liver function) -the liver synthesizes and secretes bile.
C. Formation of urea: Incorrect (this is a liver function) -the liver converts ammonia to urea (urea cycle).
D. Secretion of insulin: insulin is produced and secreted by the pancreatic β-cells, not the liver, so this is not a liver function.
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