A transplant recipient is more likely to reject a transplanted organ if there is not a close match between what of the recipient and that of the donor?
major histocompatibility complex
antibody response
blood type
sex and age
The Correct Answer is A
A. major histocompatibility complex: MHC (human leukocyte antigen, HLA) matching is critical because disparities trigger strong T-cell–mediated rejection responses.
B. antibody response: the recipient’s antibody response intensity matters clinically, but you don’t “match” antibody responses between donor and recipient; rather you try to match MHC and blood type.
C. blood type: blood type mismatches can cause hyperacute rejection and are important to consider, but MHC/HLA matching is the key determinant of long-term rejection risk.
D. sex and age: sex and age are not major determinants of graft compatibility; they are not the primary matching criteria used to reduce rejection risk.
Nursing Test Bank
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Related Questions
Correct Answer is D
Explanation
A. The presence of antibodies triggers the production of antigens: antibodies are produced in response to antigens, not the other way around.
B. Antibodies can be foreign cells, proteins, or other large molecules. Antigens are large proteins made by B cells: this reverses definitions: antigens are foreign molecules/cells that stimulate immune response; antibodies are proteins produced (by B cells) that bind antigens.
C. Antigens function to destroy or neutralize antibodies: antigens elicit antibody production; they do not act to destroy antibodies.
D. The presence of an antigen triggers the production of antibodies: antigens (foreign proteins, polysaccharides, cells) stimulate B cells to differentiate into plasma cells that produce specific antibodies.
Correct Answer is ["A","B"]
Explanation
A. Filter lymph: lymph nodes physically and biologically filter lymph, trapping pathogens and debris.
B. Immune surveillance: lymph nodes house lymphocytes and antigen-presenting cells that monitor for and respond to foreign antigens.
C. Produce macrophages: lymph nodes contain macrophages (and support their activity), but macrophages differentiate from monocytes in tissues; nodes are not typically described as producing macrophages de novo.
D. Filter blood: the spleen primarily filters blood; lymph nodes filter lymph, not systemic blood.
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