The directions for reconstitution of a medication indicate: "For IM use, add 6 mL sterile water for injection. Resulting solution contains 500 mg of medication per mL." The vial contains 3 grams of medication. How much diluent is added to the vial to prepare the medication for IM use?
6 mL
3 grams
500 mg/mL
1 mL
The Correct Answer is A
A. 6 mL: The directions explicitly instruct adding 6 mL of sterile water to the vial to achieve a final concentration of 500 mg/mL. This volume of diluent ensures proper reconstitution and accurate dosing for intramuscular administration.
B. 3 grams: This represents the total amount of medication in the vial, not the volume of diluent to be added. Confusing the total drug amount with diluent volume would result in incorrect preparation.
C. 500 mg/mL: This is the final concentration of the reconstituted solution, not the amount of diluent. It indicates the strength after adding the correct volume of sterile water.
D. 1 mL: Adding 1 mL of diluent would create a solution with a much higher concentration than intended, leading to potential dosing errors and increased risk of adverse effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Calculation:
- Identify the ordered dose and available concentration
Ordered Dose: 15 mg
Available Concentration: 30 mg/mL
- Calculate the volume to administer
Volume to administer = Ordered Dose ÷ Concentration
Volume to administer = 15 ÷ 30
= 0.5 mL
Correct Answer is A
Explanation
A. Fluid shift: Third-spacing refers to the movement of fluid from the intravascular or intracellular compartments into interstitial or potential spaces where it is physiologically unavailable. This can lead to hypovolemia, edema, and decreased tissue perfusion. Common causes include burns, severe infections, and liver or kidney disease.
B. Fluid transfer: Fluid transfer is a nonspecific term and does not capture the pathophysiologic concept of fluid accumulation in nonfunctional compartments. It lacks the clinical significance associated with third-spacing.
C. Fluid retention: Fluid retention generally refers to the overall accumulation of fluid in the body, often within the vascular or interstitial space, but does not specifically describe fluid sequestered in a third space.
D. Fluid expansion: Fluid expansion refers to increasing circulating volume, often through intravenous fluid administration. It does not describe the pathological movement of fluid into compartments where it is unavailable for normal physiologic use.
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