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The directions for reconstitution of oxacillin sodium for injection are on the drug label. Directions read: "For IM use, add 5.7mt sterile water for injection Resulting solution contains 250 mg oxacillin sodium per 1.5 mL. The vial contains oxacillin sodium equivalent to 1 gram. Usual adult dosage of oxacillin sodium is 250 mg-500 mg IM every 4 to 6 hours." The patient/client is to receive 400 mg IM every 6 hours. How many milliliters would the nurse administer?

A.

5.7 mL/dose

B.

1.7 mL/dose

C.

2.4 mL/dose

D.

2.1 mL/dose

Answer and Explanation

The Correct Answer is C

Step 1: Interpret the concentration

  • After reconstitution, the solution contains 250 mg per 1.5 mL.
  • This means: 250 ÷ 1.5 = 166.7 mg per mL.

Step 2: Calculate the volume needed for 400 mg

  • Ordered dose = 400 mg.
  • Concentration = 166.7 mg per mL.
  • Volume = 400 ÷ 166.7 ≈ 2.4 mL.


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Related Questions

Correct Answer is C

Explanation

A. Insert needle through side of stopper and draw medication into the barrel:The needle must be inserted straight through the center of the rubber stopper, not the side, to ensure the seal integrity is maintained and prevent coring (cutting out a piece of the stopper).

B. Pull back on the syringe's plunger and fill the barrel completely with the medication:Pulling back the plunger and filling the barrel completely (i.e., administering 3 mL in a 3-mL syringe) is not always correct; the volume should only match the dose ordered by the physician.

C. Draw an amount of air into the syringe equal to medication needed:To ensure easy withdrawal of the liquid medication and to prevent a vacuum from forming inside the vial (which makes withdrawal difficult), an equal volume of air must be injected into the vial first.

Remove the cover from the vial and clean with soapy water:The rubber stopper must be cleaned with an antiseptic swab (e.g., alcohol swab), not soapy water, before the needle is inserted. The protective cap is usually removed and the swab applied.

Correct Answer is A

Explanation

Dimensional analysis:

  • Ordered dose: 8 mg IM.
  • Available concentration: 5 mg per 1 mL.
  • Volume needed = 8 mg × (1 mL / 5 mg) = 1.6 mL.

A. 3 mL:A 3 mL syringe is appropriate for IM injections and can accurately deliver 1.6 mL. It provides clear mL markings and enough capacity for the dose.

B. Insulin U-100:Insulin syringes are calibrated in insulin units, not mL, and are designed for subcutaneous insulin, not IM lorazepam.

C. Insulin U-50:Same issue as U-100; calibrated in units and not appropriate for IM medication administration.

D. 1 mL:A 1 mL syringe cannot hold the required 1.6 mL volume, so it is insufficient for this dose.

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