The infant's anterior

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becomes sunken during severe dehydration but appears normal when hydrated.

A. Hypotonic solution: Hypotonic fluids cause water to move into cells, which may lead to cellular swelling or hemolysis if infused improperly. They do not directly cause tissue necrosis, blistering, or ulceration at the IV site. Local tissue injury of this severity is not typical.

B. Vitamin infusion: Most vitamin infusions are considered non-vesicant and are diluted to reduce irritation. While mild local irritation may occur, they do not produce the severe tissue damage associated with blistering or ulceration. Tissue necrosis is not an expected effect.

C. Vesicant: Vesicant medications cause severe tissue injury if they leak into surrounding tissue. Extravasation can result in blistering, ulceration, necrosis, and long-term tissue damage due to direct cytotoxic effects. Immediate intervention is required when vesicant extravasation is suspected.

D. Isotonic fluid: Isotonic fluids have a similar osmolarity to plasma and are generally well tolerated by peripheral veins. They do not disrupt cellular integrity or cause local tissue destruction. Blistering and ulceration are not associated with isotonic IV solutions.

A. 12/16/25: Counting 7 days from 12/08/25 and including the start date results in a 7-day course ending on 12/15/25, not 12/16/25. Selecting 12/16/25 would extend the therapy by one extra day.

B. 12/08/25: The start date is 12/08/25; terminating on the same day would only allow a single dose, which does not complete the prescribed 7-day regimen.

C. 12/15/25: A 7-day course beginning on 12/08/25 concludes on 12/15/25. This includes the initial dose on 12/08/25 and provides the full duration of therapy as ordered.

D. 12/25/25: Ending on 12/25/25 would result in a 17-day course, exceeding the prescribed duration. This would lead to unnecessary antibiotic exposure and increase the risk of adverse effects or resistance.