The loose-fitting sac around the heart is the:

It explains that the primary immune response produces antibodies within five to ten days of exposure to antigens, while the secondary immune response produces antibodies within a day or two of subsequent exposure to the same antigen.
This is because the primary immune response involves the activation and differentiation of naive B cells into plasma cells and memory cells, while the secondary immune response involves the rapid activation of memory cells into plasma cells.
Choice A is wrong because the primary and secondary immune responses can occur in both children and adults.
Choice B is wrong because the primary immune response is slower than the secondary immune response in producing antibodies.
Choice D is wrong because both primary and secondary immune responses are important for the body’s ability to protect itself from pathogens.
The primary immune response generates immunological memory, while the secondary immune response provides a faster and stronger response to repeated infections.

The endocardium is the thin inner lining of the heart chambers and also forms the surface of the heart valves.
Some possible explanations for the other choices are:
Choice A is wrong because the pericardium is the sac that surrounds the heart and consists of two layers: the fibrous pericardium and the serous pericardium.
Choice C is wrong because the myocardium is the thick middle layer of muscle that allows the heart chambers to contract and relax to pump blood to the body.
Choice D is wrong because epicardium is another name for the visceral layer of the serous pericardium that is fused to the heart and is part of the heart wall.