The nurse recognizes that patients with von Willebrand disease are at risk for prolonged bleeding times for which reason?
Adequate platelet production.
Deficiency in intrinsic clotting system factor.
Impairment of the thrombin fibrinogen reaction.
Variable factor VIII deficiencies and platelet dysfunction.
The Correct Answer is D
Choice A rationale:
Adequate platelet production does not explain the prolonged bleeding times in von Willebrand disease. These patients often have normal platelet counts, but their platelets do not function properly due to the absence or dysfunction of von Willebrand factor.
Choice B rationale:
Deficiency in intrinsic clotting system factor is not the primary cause of prolonged bleeding times in von Willebrand disease. The deficiency or dysfunction of von Willebrand factor, a protein that helps platelets adhere to the blood vessel walls and clot properly, is the key issue in this disorder.
Choice C rationale:
Impairment of the thrombin fibrinogen reaction does not directly relate to von Willebrand disease. This disorder primarily involves platelet dysfunction and variable factor VIII deficiencies, leading to prolonged bleeding times.
Choice D rationale:
Variable factor VIII deficiencies and platelet dysfunction are characteristic of von Willebrand disease. Factor VIII helps with blood clotting, and its deficiency, along with impaired platelet function, contributes to the prolonged bleeding times in patients with von Willebrand disease.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
Metabolic acidosis is characterized by low blood pH and low bicarbonate ion levels. In this case, the patient has a high bicarbonate ion level (25 mEq/L), indicating a compensatory response to respiratory acidosis. Metabolic alkalosis, on the other hand, would present with high pH and high bicarbonate ion levels.
Choice B rationale:
Metabolic alkalosis is characterized by high blood pH and high bicarbonate ion levels. The patient's bicarbonate ion level (25 mEq/L) is within the normal range, and the low pH and high PaCO2 (49 mm Hg) indicate respiratory acidosis, not metabolic alkalosis.
Choice C rationale:
Respiratory acidosis is characterized by low blood pH and high partial pressure of carbon dioxide (PaCO2) levels. In this case, the patient has a low pH (7.29) and elevated PaCO2 (49 mm Hg), indicating respiratory acidosis. The elevated bicarbonate ion level (25 mEq/L) is a compensatory response. Respiratory alkalosis would present with high pH and low PaCO2 levels.
Choice D rationale:
Respiratory alkalosis is characterized by high blood pH and low PaCO2 levels. The patient's PaCO2 level is elevated (49 mm Hg), indicating respiratory acidosis, not alkalosis. The low pH (7.29) further supports the diagnosis of respiratory acidosis.
Correct Answer is D
Explanation
The correct answer is Choice D. Then start with Choice A rationale:
Choice A is incorrect because it representsmetabolic alkalosis, not respiratory alkalosis. Metabolic alkalosis occurs when there is a primary increase in the bicarbonate (HCO3) level, which causes the pH to rise above the normal range (7.35-7.45). The PaCO2 is normal in this case, indicating that the respiratory system is not involved in the acid-base imbalance.Some causes of metabolic alkalosis include vomiting, diuretic use, excessive antacid intake, and mineralocorticoid excess1.
Choice B is incorrect because it representsrespiratory acidosis, not respiratory alkalosis. Respiratory acidosis occurs when there is a primary decrease in the PaCO2 level, which causes the pH to fall below the normal range. The HCO3 is normal in this case, indicating that the metabolic system is not involved in the acid-base imbalance.Some causes of respiratory acidosis include hypoventilation, airway obstruction, chest trauma, neuromuscular disorders, and chronic lung diseases2.
Choice C is incorrect because it representsmetabolic acidosis, not respiratory alkalosis. Metabolic acidosis occurs when there is a primary decrease in the HCO3 level, which causes the pH to fall below the normal range. The PaCO2 is normal in this case, indicating that the respiratory system is not involved in the acid-base imbalance.Some causes of metabolic acidosis include diabetic ketoacidosis, lactic acidosis, renal failure, diarrhea, and poisoning3.
Choice D is correct because it representsrespiratory alkalosis. Respiratory alkalosis occurs when there is a primary decrease in the PaCO2 level, which causes the pH to rise above the normal range. The HCO3 is normal in this case, indicating that the metabolic system is not involved in the acid-base imbalance. Some causes of respiratory alkalosis include hyperventilation, anxiety, panic, fever, pain, tumor, trauma, severe anemia, liver disease, overdose of certain medicines, pulmonary embolism, pregnancy, and any lung disease that leads to shortness of breath . Respiratory alkalosis is characterized by symptoms such as breathlessness, dizziness, numbness, tingling, muscle spasms, chest discomfort, confusion, and fainting.
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