What is the consequence of intrinsic factor not binding to vitamin B12?
Vitamin B12 is stored in excess in the liver.
Vitamin B12 is not absorbed and can lead to deficiency.
Vitamin B12 is converted to its inactive form.
Vitamin B12 is excreted through the respiratory system.
The Correct Answer is B
A. Vitamin B12 is stored in excess in the liver: Without intrinsic factor, the vitamin cannot reach the liver for storage.
B. Vitamin B12 is not absorbed and can lead to deficiency: Intrinsic factor is the "key" that allows Vitamin B12 to be absorbed in the ileum; without it, the vitamin passes through the GI tract and is excreted in feces.
C. Vitamin B12 is converted to its inactive form: The vitamin is not chemically inactivated; it simply remains in the lumen of the intestine because it cannot be transported across the membrane.
D. Vitamin B12 is excreted through the respiratory system: Vitamins are not gases and cannot be excreted via the lungs.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Muscle weakness: This is more common in hypercalcemia or hypokalemia.
B. Chvostek's sign: A serum calcium of 7.5 mg/dL is low (normal is 9–10.5 mg/dL). Hypocalcemia causes neuromuscular irritability. Chvostek’s sign (facial twitching when the facial nerve is tapped) is a classic finding.
C. Constipation: Constipation is a sign of hypercalcemia. Hypocalcemia often causes increased GI motility (diarrhea).
D. Hypertension: Hypocalcemia is more likely to be associated with hypotension and cardiac arrhythmias.
Correct Answer is B
Explanation
A. It enhances the metabolism of vitamin B12: Intrinsic factor is strictly for transport and absorption, not metabolism in the liver.
B. It leads to decreased absorption of vitamin B12, causing deficiency: Vitamin B12 cannot cross the intestinal lining in the ileum on its own; it must be bound to intrinsic factor to be recognized and absorbed.
C. It boosts the storage of vitamin B12 in muscle tissues: B12 is primarily stored in the liver, and intrinsic factor does not affect storage mechanisms.
D. It increases the excretion of vitamin B12 through urine: If B12 isn't absorbed, it is excreted in the stool, not the urine.
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