What is the generic name of Plaquenil?
Pantoprazole
Hydrocodone bitartrate with acetaminophen
Hydroxychloroquine sulfate
Prednisolone acetate
The Correct Answer is C
A. Pantoprazole is the generic name for the brand Protonix, a proton pump inhibitor. It irreversibly binds to the hydrogen-potassium ATPase enzyme system at the secretory surface of gastric parietal cells. It is used to treat erosive esophagitis and hypersecretory conditions.
B. Hydrocodone bitartrate with acetaminophen is the generic combination found in brands like Vicodin or Lortab. It combines an opioid agonist with a non-opioid analgesic to manage moderate to severe pain. It is not the active constituent in Plaquenil.
C. Hydroxychloroquine sulfate is the generic name for Plaquenil, an aminoquinoline derivative. It interferes with digestive vacuole function within sensitive malarial parasites and inhibits rheumatoid factor and acute phase reactants. This medication is indicated for systemic lupus erythematosus and rheumatoid arthritis.
D. Prednisolone acetate is a glucocorticoid often found in ophthalmic suspensions such as Pred Forte. It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing increased capillary permeability. It is a steroid, not a disease-modifying antirheumatic aminoquinoline.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Olanzapine does not possess pharmacological activity within the medullary cough center or peripheral stretch receptors. It lacks the properties of an antitussive agent such as benzonatate or codeine. It is not indicated for the suppression of a cough reflex.
B. This compound does not function as an antiarrhythmic by modulating cardiac ion channels. It lacks the specific electrophysiological effects required for classes 1 through 4 of the Vaughan Williams classification. It is not used to treat atrial or ventricular arrhythmias.
C. Olanzapine is a second-generation atypical antipsychotic that antagonizes dopamine D2 and serotonin 5-HT2A receptors. It is clinically indicated for the treatment of schizophrenia and bipolar 1 disorder. This mechanism effectively modulates mesolimbic and mesocortical dopaminergic pathways in the brain.
D. Although olanzapine may reduce agitation associated with psychiatric disorders, it is not primarily classified as an anxiolytic. It lacks the specific benzodiazepine or buspirone-like mechanisms typically utilized for generalized anxiety disorder. Its primary therapeutic designation remains within the antipsychotic class.
Correct Answer is B
Explanation
A. Prozac is the proprietary brand name for fluoxetine, a selective serotonin reuptake inhibitor. It is chemically distinct from citalopram due to its specific phenylpropylamine structure and long-acting metabolite norfluoxetine. It is not the brand name for citalopram hydrobromide.
B. Celexa is the brand name for citalopram hydrobromide, a highly selective serotonin reuptake inhibitor. It increases synaptic serotonin levels by inhibiting the presynaptic transporter protein in the central nervous system. This pharmacological action is utilized to treat major depressive disorder.
C. Lexapro is the brand name for escitalopram, which is the pure S-enantiomer of the racemic mixture citalopram. While it shares a similar chemical scaffold, it provides higher potency at the serotonin transporter site. It is a distinct product from Celexa.
D. Effexor is the brand name for venlafaxine, which belongs to the serotonin-norepinephrine reuptake inhibitor class. It inhibits the reuptake of both serotonin and norepinephrine neurotransmitters in a dose-dependent manner. It is not a brand name for the medication citalopram.
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