Which condition is associated with postural instability and "pill-rolling" tremors?
Alzheimer's disease
Parkinson's disease
Huntington's disease
Multiple sclerosis
The Correct Answer is B
A. Alzheimer's disease. : This neurodegenerative condition is defined by progressive cortical atrophy leading to significant cognitive and memory impairment. While late-stage patients may develop gait changes, they do not exhibit the classic rhythmic resting tremor. It is primarily a dementing illness.
B. Parkinson's disease. : The loss of dopaminergic inhibition in the basal ganglia leads to the characteristic 4 to 6 Hz resting tremor. Postural instability occurs due to the loss of righting reflexes and truncal rigidity. These are core clinical motor features.
C. Huntington's disease. : This genetic disorder is characterized by chorea, which consists of involuntary, jerky, and rapid movements. It differs significantly from the slow, rhythmic pill-rolling resting tremor seen in parkinsonism. It involves the degeneration of the caudate nucleus.
D. Multiple sclerosis. : This condition often presents with intention tremors, which occur during purposeful movement rather than at rest. While it can cause ataxia and gait imbalances, it lacks the specific resting tremor of basal ganglia origin. It is a white matter disease.
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Related Questions
Correct Answer is D
Explanation
A. cholecystitis. : This medical term specifically denotes the acute or chronic inflammation of the gallbladder wall. While often caused by gallstones, it refers to the inflammatory response rather than the stones themselves. It describes a clinical state of infection or irritation.
B. diverticulitis. : This refers to the inflammation or infection of small pouches known as diverticula in the digestive tract. It is typically a colonic pathology unrelated to the biliary system. It does not involve the formation of calculi within the gallbladder.
C. diverticulosis. : This condition describes the presence of multiple outpouchings in the muscular layer of the gastrointestinal wall. It is an asymptomatic structural change usually found in the sigmoid colon. It does not refer to biliary calculi or gallbladder disease.
D. cholelithiasis. : This term is derived from Greek roots meaning gallbladder and stone formation. It specifically identifies the presence of solid concretions within the gallbladder lumen. This is the precise scientific designation for the condition of having gallstones.
Correct Answer is D
Explanation
A. storage and release of bile.: This physiological role is performed exclusively by the gallbladder, which concentrates and stores bile produced by the liver. The pancreas does not possess the anatomical structures for biliary storage. It only shares the common bile duct terminal.
B. detoxification of drugs and alcohol.: This metabolic process is the functional responsibility of the hepatic microsomal enzyme systems. The pancreas lacks the specialized hepatocytes and enzymes required for the biotransformation of systemic toxins. Its primary roles are digestive and endocrine.
C. conversion of bilirubin and production of cholesterol.: These biochemical activities are localized within the liver, where bilirubin is conjugated for excretion and cholesterol is synthesized. The pancreas does not participate in the metabolism of heme breakdown products. These are distinct hepatic metabolic pathways.
D. pancreatic enzyme secretion and insulin production.: This organ functions as a dual gland, providing exocrine digestive enzymes like lipase and amylase. Simultaneously, the endocrine Islets of Langerhans secrete hormones such as insulin and glucagon into the blood. This maintains both digestion and glucose regulation.
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