Which of the following is a long-term complication associated with uncontrolled diabetes mellitus?

Insulin is a hormone produced by the pancreas that plays a crucial role in regulating blood glucose levels. It facilitates glucose uptake into cells, promotes glycogen synthesis in the liver and muscles, and inhibits hepatic glucose production.

Incorrect choices:

a. This choice is incorrect. Glucagon is another pancreatic hormone that increases blood glucose levels by promoting glycogen breakdown and glucose release from the liver.

c. This choice is incorrect. Epinephrine is a hormone produced by the adrenal glands that can raise blood glucose levels during times of stress.

d. This choice is incorrect. Cortisol, also produced by the adrenal glands, can increase blood glucose levels in response to stress and inflammation.

Chronic hyperglycemia in diabetes mellitus can lead to damage of small blood vessels and nerves, resulting in neuropathy characterized by numbness, tingling, and pain in the extremities.

Incorrect choices:

a. This choice is incorrect. Nausea, vomiting, and abdominal pain are not typically manifestations of neuropathy in diabetes mellitus.

b. This choice is incorrect. Blurred vision and vision loss are associated with diabetic retinopathy, a microvascular complication, not nerve damage.

c. This choice is incorrect. Impaired wound healing and increased susceptibility to infections are related to the effects of hyperglycemia on blood flow and immune function, rather than nerve damage.