Which of the following is a therapuetic drug class for olanzapine?
Antitussive
Antiarrhythmic
Antipsychotic
Anxiolytic
The Correct Answer is C
A. Olanzapine does not possess pharmacological activity within the medullary cough center or peripheral stretch receptors. It lacks the properties of an antitussive agent such as benzonatate or codeine. It is not indicated for the suppression of a cough reflex.
B. This compound does not function as an antiarrhythmic by modulating cardiac ion channels. It lacks the specific electrophysiological effects required for classes 1 through 4 of the Vaughan Williams classification. It is not used to treat atrial or ventricular arrhythmias.
C. Olanzapine is a second-generation atypical antipsychotic that antagonizes dopamine D2 and serotonin 5-HT2A receptors. It is clinically indicated for the treatment of schizophrenia and bipolar 1 disorder. This mechanism effectively modulates mesolimbic and mesocortical dopaminergic pathways in the brain.
D. Although olanzapine may reduce agitation associated with psychiatric disorders, it is not primarily classified as an anxiolytic. It lacks the specific benzodiazepine or buspirone-like mechanisms typically utilized for generalized anxiety disorder. Its primary therapeutic designation remains within the antipsychotic class.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Rizatriptan is the active pharmaceutical ingredient for the brand Maxalt. While it belongs to the same selective 5-hydroxytryptamine 1B and 1D receptor agonist class, it is not the chemical constituent of Imitrex. It possesses a different pharmacokinetic profile.
B. Almotriptan is the generic name for the brand Axert. This compound is indicated for the acute treatment of migraine with or without aura in adults. It is a separate molecular entity from the drug requested in the question stem.
C. Sumatriptan is the generic name for Imitrex, the first triptan developed for clinical use. It acts as a selective agonist at vascular 5-HT1B and 5-HT1D receptors. This binding induces cranial vessel vasoconstriction and inhibits the release of proinflammatory neuropeptides.
D. Eletriptan is marketed under the brand name Relpax. It is a second-generation triptan used for migraine abortive therapy. It is not the active ingredient in Imitrex. Its metabolism and bioavailability differ significantly from those of sumatriptan.
Correct Answer is C
Explanation
A. Focalin is the brand name for dexmethylphenidate, which is the d-threo-enantiomer of methylphenidate. It acts primarily as a dopamine and norepinephrine reuptake inhibitor. It does not contain the sulfate or saccharate salts of the amphetamine molecule found in the question.
B. Vyvanse contains lisdexamfetamine dimesylate, a prodrug converted to dextroamphetamine in the blood. While it provides dextroamphetamine, it is a single-molecule formulation rather than a mixture of salts. It lacks the levoamphetamine component found in the mixed salt combination.
C. Adderall is the proprietary name for a combination of 4 different amphetamine salts. It specifically consists of dextroamphetamine saccharate, dextroamphetamine sulfate, amphetamine aspartate monohydrate, and amphetamine sulfate. This mixture provides a specific ratio of 3 to 1 dextroamphetamine to levoamphetamine.
D. Ritalin is the brand name for methylphenidate hydrochloride, a central nervous system stimulant. Its mechanism involves the inhibition of the dopamine transporter and norepinephrine transporter. It is chemically distinct from the phenethylamine derivatives found in amphetamine and dextroamphetamine salt mixtures.
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