Which of the following is an exogenous cause of Cushing's syndrome?
Lung tumor
Adrenal carcinoma
Long-term use of glucocorticoids
Pituitary tumor
The Correct Answer is C
Rationale:
A. Lung tumor: A lung tumor, especially small-cell carcinoma, can secrete ectopic ACTH, stimulating the adrenal glands to produce excess cortisol. This is considered an endogenous cause of Cushing’s syndrome rather than an exogenous source.
B. Adrenal carcinoma: Adrenal tumors can directly increase cortisol production without regulation by ACTH. This is another endogenous cause of Cushing’s syndrome and is not related to external factors.
C. Long-term use of glucocorticoids: Prolonged administration of glucocorticoid medications, such as prednisone, is the most common exogenous cause of Cushing’s syndrome. These drugs mimic cortisol activity and suppress normal hypothalamic-pituitary-adrenal function, leading to iatrogenic Cushing’s.
D. Pituitary tumor: A pituitary adenoma producing excess ACTH leads to overstimulation of the adrenal glands and high cortisol levels. This represents an endogenous cause of Cushing’s syndrome known as Cushing’s disease.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Rationale:
A. Wear compression stockings daily: Compression stockings are helpful for venous insufficiency or preventing deep vein thrombosis, but they do not prevent complications such as retinopathy and nephropathy, which are directly related to vascular changes
B. Maintain stable blood glucose levels: Chronic hyperglycemia damages small blood vessels, leading to microvascular complications including retinopathy and nephropathy. Maintaining stable blood glucose levels slows disease progression and is the most effective preventive strategy.
C. Have an eye examination once per year: Annual eye exams are important for early detection of diabetic retinopathy but do not directly prevent its development. Preventive measures must focus on glucose control to minimize vascular injury before it occurs.
D. Examine your feet carefully every day: Daily foot inspection is essential for preventing peripheral neuropathy complications such as ulcers and infections. However, this practice is not directly related to preventing retinopathy or nephropathy.
Correct Answer is A
Explanation
Rationale:
A. Flexing her knees and feet frequently: Regular movement of the legs improves venous return and decreases stasis, which helps prevent clot extension and recurrence. This is an important teaching point for clients recovering from DVT while on anticoagulant therapy.
B. Taking an NSAID tablet daily: NSAIDs increase the risk of bleeding when combined with anticoagulants because they inhibit platelet function and irritate the gastrointestinal lining. Clients on anticoagulant therapy should avoid NSAIDs.
C. Wearing loose, non-constricting stockings: Compression stockings, not loose ones, are recommended to reduce venous stasis, improve circulation, and decrease the risk of post-thrombotic syndrome. Loose stockings do not provide the needed benefit for DVT.
D. Applying cool compresses to her legs: Cool compresses may provide temporary comfort but do not help with circulation or prevention of complications. Warm compresses are sometimes used for symptom relief, but they are not a primary discharge teaching point.
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