Which of the following is the most likely cause of gastroesophageal reflux disease (GERD)?
Rapid gastric emptying
Hyposecretion of gastric acid
Weakness of the lower esophageal sphincter
Decreased intra-abdominal pressure
The Correct Answer is C
A. Rapid gastric emptying. : Also known as dumping syndrome, this involves the quick movement of chyme into the duodenum. It usually causes osmotic diarrhea and vasomotor symptoms rather than reflux. It does not facilitate the retrograde movement of acid into the esophagus.
B. Hyposecretion of gastric acid. : Low levels of hydrochloric acid would theoretically reduce the caustic nature of refluxate if it occurred. GERD is more commonly associated with normal or high acid production. It is not a primary mechanical cause of the disease.
C. Weakness of the lower esophageal sphincter. : Incompetence of this muscular ring allows the retrograde flow of gastric contents into the esophageal lumen. Transient relaxations or low resting pressure diminish the barrier against acidic chyme. This is the primary pathophysiological mechanism of reflux.
D. Decreased intra-abdominal pressure. : Lowered pressure in the abdominal cavity would actually reduce the force pushing gastric contents upward. Increased pressure, such as in obesity or pregnancy, is what exacerbates reflux. Decreased pressure does not contribute to the failure of the sphincter.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. A type of generalized seizure involving loss of consciousness: This describes an absence or tonic-clonic seizure where cortical involvement is bilateral from the onset. An aura is specifically a focal phenomenon that may or may not generalize. It represents localized neuronal discharge.
B. A fear of having a seizure: While anxiety may occur, an aura is a distinct neurological event caused by abnormal electrical activity in a specific brain region. It is a physiological symptom rather than a purely psychological state. It is not an emotional phobia.
C. A postictal period characterized by confusion and fatigue: This interval occurs after the seizure has ceased and the brain is recovering from metabolic exhaustion. An aura happens at the beginning of the ictal event. They are at opposite ends of the seizure timeline.
D. A brief visual or auditory sensation immediately prior to a seizure: These sensory hallucinations represent a focal aware seizure originating in the temporal or occipital lobes. They serve as a clinical warning that a larger seizure may be imminent. It is the initial manifestation of ictus.
Correct Answer is C
Explanation
A. improved digestion.: The erosion of the protective mucosal layer and subsequent tissue damage actually impair the normal mechanical and chemical processes of the stomach. Ulceration leads to dyspepsia and delayed gastric emptying. It does not enhance the physiological breakdown of nutrients.
B. decreased abdominal pain.: Exposure of the underlying submucosa to gastric acid typically causes significant epigastric distress or burning sensations. While some food may temporarily buffer acid, the disease progression generally increases nociceptive signaling. It is a primary cause of chronic abdominal discomfort.
C. gastric hemorrhage.: Ulcers that erode into the muscularis mucosae can breach the walls of submucosal blood vessels. This results in occult bleeding or massive hematemesis and melena, depending on the vessel size. This represents a frequent and life-threatening complication of the disease.
D. increased production of intrinsic factor.: Chronic inflammation, particularly from H. pylori or autoimmune gastritis, often leads to the atrophy of parietal cells. This causes a decrease in the secretion of this glycoprotein required for Vitamin B12 absorption. It does not stimulate secretory upregulation.
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