Which of the following skin changes is a hallmark of chronic psoriasis?

Explanation: Psoriasis is an autoimmune disorder in which T-cells, a type of white blood cell, become overactive and trigger an inflammatory response. These T-cells promote the rapid growth of skin cells, leading to the characteristic plaques seen in psoriasis.

Incorrect choices: b. B-cells: While B-cells are important components of the immune system, they are not primarily involved in the etiology of psoriasis. T-cells are the central players in the autoimmune response seen in psoriasis.

c. Platelets: Platelets are primarily responsible for blood clotting and are not directly related to the development of psoriasis.

d. Eosinophils: Eosinophils are a type of white blood cell involved in immune responses against parasitic infections and allergic reactions. While they are important in certain immune processes, they are not the main players in psoriasis etiology.

Explanation: Keeping the skin well-hydrated is essential in managing psoriasis. Patients should use fragrance-free moisturizers to prevent skin dryness and irritation, which can trigger flare-ups.

Incorrect choices: a. "Avoid using moisturizers, as they can worsen psoriasis flare-ups." - This statement is incorrect. Moisturizers are important for managing psoriasis symptoms and preventing dryness and irritation.

b. "Take hot baths with scented soaps to soothe the skin." - Hot baths and scented soaps can actually worsen psoriasis symptoms and should be avoided.

d. "Expose your skin to direct sunlight for prolonged periods to improve symptoms." - While some sunlight exposure may benefit psoriasis, prolonged and direct exposure can lead to skin damage and increase the risk of skin cancer. Sun exposure should be limited and done with caution.