Which statement best describes a depot medication?
A hydrophilic medication that is not able to cross the blood-brain-barrier.
An intramuscular injection that is released slowly over a long period of time.
A tablet that is placed under the tongue in order to be absorbed quickly.
A capsule that is formulated for a sustained release.
The Correct Answer is B
A. A hydrophilic medication that is not able to cross the blood-brain barrier: Hydrophilic drugs do not easily pass through lipid membranes like the blood-brain barrier, but this property does not define a depot medication which are characterized by prolonged release, not solubility or blood-brain barrier permeability.
B. An intramuscular injection that is released slowly over a long period of time: Depot medications are typically given intramuscularly or subcutaneously and formulated to release the active drug gradually. This provides sustained therapeutic effects over days or weeks, improving adherence and maintaining stable drug levels.
C. A tablet that is placed under the tongue in order to be absorbed quickly: Sublingual tablets are designed for rapid absorption through the oral mucosa, bypassing first-pass metabolism. This route provides immediate effects, which is the opposite of the slow, sustained action seen with depot medications.
D. A capsule that is formulated for a sustained release: Although sustained-release capsules also allow gradual drug absorption, they are taken orally and work through controlled dissolution. Depot medications differ in that they are injectable and create a long-lasting drug reservoir within body tissues.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. To improve mental alertness and focus: Kava does not enhance alertness or cognitive focus. In fact, it has sedative properties that may cause drowsiness, making it unsuitable for improving attention or concentration.
B. To lower cholesterol and triglycerides: Kava has no established lipid-lowering effects. Herbal remedies for cholesterol management typically include garlic or red yeast rice, not kava, which primarily acts on the central nervous system.
C. To reduce muscle cramps and injury: Kava does not have muscle relaxant or anti-inflammatory properties effective for treating cramps or preventing injuries. Its mechanism targets anxiety and sleep regulation rather than musculoskeletal issues.
D. To promote sleep and reduce anxiety: Kava is commonly used as an herbal supplement for its anxiolytic and sedative effects. It enhances GABA receptor activity in the brain, helping reduce anxiety, promote relaxation, and improve sleep quality.
Correct Answer is A
Explanation
A. An adverse medication effect resulting in blistering and peeling of skin: Stevens-Johnson syndrome is a rare but severe hypersensitivity reaction often triggered by medications. It is characterized by painful blistering, peeling of the skin, and involvement of mucous membranes.
B. An adverse medication effect resulting in a yellow discoloration of the eyes: Yellowing of the eyes indicates jaundice, which is commonly linked to hepatotoxicity. While some drugs can cause liver injury, this finding does not describe Stevens-Johnson syndrome.
C. An adverse medication effect resulting in nephrotoxicity and reduced urine output: Nephrotoxicity is kidney-related damage that reduces renal function. Certain drugs such as aminoglycosides can cause this, but it is unrelated to the dermatologic presentation of Stevens-Johnson syndrome.
D. An adverse medication effect resulting in pulmonary toxicity and hypoxemia: Pulmonary toxicity can occur with medications such as amiodarone, leading to hypoxemia, but this does not describe Stevens-Johnson syndrome, which primarily affects the skin and mucous membranes.
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