A 24-year-old woman with a history of major depressive disorder treated with sertraline is brought to the emergency department by her partner for evaluation of fever, vomiting, and weakness. In the emergency department, her temperature is 103°F, her heart rate is 129 beats per minute, she is agitated and restless, and she displays hyperactive reflexes. Her symptoms began several hours after she used a new medication prescribed by her primary care provider. Which of the following is most likely to be the new medication?
Propranolol
Topiramate
Sumatriptan
Naproxen
The Correct Answer is C
Choice A reason: Propranolol is a beta-blocker used for anxiety, hypertension, and migraine prophylaxis. It does not increase serotonin levels and is not associated with serotonin syndrome, making it an unlikely cause of the described symptoms.
Choice B reason: Topiramate is an anticonvulsant and mood stabilizer used for epilepsy and migraine prevention. It does not significantly affect serotonin pathways and is not known to cause serotonin syndrome.
Choice C reason: Sumatriptan is a serotonin receptor agonist used for acute migraine treatment. When combined with SSRIs like sertraline, it can precipitate serotonin syndrome—a potentially life-threatening condition characterized by hyperthermia, autonomic instability, neuromuscular abnormalities, and altered mental status. The timing and symptoms strongly suggest this interaction.
Choice D reason: Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used for pain and inflammation. It does not interact with serotonergic systems and is not associated with serotonin syndrome.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: This is an open-ended question that invites further discussion. It is exploratory, not summarizing.
Choice B reason: This is a reflective statement that validates the client’s insight and emotional experience. It is supportive but not a summary of the client’s narrative.
Choice C reason: This is a clear summarizing statement. It encapsulates the client’s motivations, experiences, and evolving understanding of alcohol’s impact. It reflects back the client’s narrative in a structured and comprehensive way.
Choice D reason: This is a brief reflection that captures part of the client’s experience. However, it lacks the depth and structure of a full summary.
Correct Answer is A
Explanation
Choice A reason: Carbamazepine is associated with significant teratogenic risks, including neural tube defects and craniofacial abnormalities. It is contraindicated in pregnancy due to its potential to cause congenital malformations, especially during the first trimester.
Choice B reason: Lurasidone has limited data on teratogenicity but is generally considered safer than mood stabilizers like carbamazepine. It is often used cautiously in pregnancy when benefits outweigh risks.
Choice C reason: Lamotrigine is considered one of the safer mood stabilizers during pregnancy. It has not been strongly associated with major congenital malformations and is often preferred for bipolar maintenance in pregnant patients.
Choice D reason: Quetiapine is an atypical antipsychotic with a relatively low teratogenic risk profile. It is frequently used in pregnancy for mood stabilization due to its favorable safety data.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.
