A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil (Viagra). He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?

Reduced effectiveness of the sildenafil

Significant decrease in blood pressure

Significant increase in pulse rate

Increased risk of bleeding

Answer and Explanation

The Correct Answer is B

A. Reduced effectiveness of the sildenafil: Sildenafil’s effect is not the primary concern when combined with nitrates; the interaction is about additive vasodilation rather than sildenafil becoming ineffective.
B. Significant decrease in blood pressure: Combining sildenafil (a PDE-5 inhibitor) with nitrates causes marked vasodilation that can produce a dangerous drop in blood pressure (severe hypotension), which is why coadministration is contraindicated.
C. Significant increase in pulse rate: Although reflex tachycardia can occur with hypotension, the main clinically significant and consistently reported problem with sildenafil + nitrates is large decreases in blood pressure rather than a primary sustained pulse increase.
D. Increased risk of bleeding: There is no direct mechanism by which sildenafil combined with nitrates causes increased bleeding risk; the major safety issue is hypotension.

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Free Nursing Study Resources

Correct Answer is ["2"]

Explanation

1,200,000units÷600,000units/mL=2mL.

A. "Dietary supplements may be expensive and are not typically covered by insurance." B. "Dietary supplements have not been tested and approved by the government." C. "Dietary supplements can cause a drug-drug interaction with nitrates." D. "There is not enough evidence that dietary supplements are effective for erectile dysfunction."

Correct Answer is C

Explanation

A. "Dietary supplements may be expensive and are not typically covered by insurance.": Cost and lack of insurance coverage are true for many supplements, but this is not the most critical safety point when the client is taking nitrates.
B. "Dietary supplements have not been tested and approved by the government.": Dietary supplements are regulated differently than prescription drugs and do not require FDA preapproval for efficacy, but this statement is general and not the most immediate safety concern for a client on nitrates.
C. "Dietary supplements can cause a drug-drug interaction with nitrates.": Some over-the-counter “sexual enhancement” or herbal products have been found to contain undeclared PDE-5 inhibitors (for example, sildenafil) or analogs; those hidden ingredients can dangerously interact with nitrates (e.g., nitroglycerin) and cause severe hypotension -this is the most important safety point to emphasize.
D. "There is not enough evidence that dietary supplements are effective for erectile dysfunction.": Many supplements lack strong evidence of benefit, but the immediate and potentially life-threatening interaction risk with nitrates is a higher-priority safety concern for this patient.

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A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil (Viagra). He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Correct Answer is ["2"]

Explanation

A nurse is providing teaching about dietary supplements to a client who has erectile dysfunction and has been prescribed nitroglycerin. Which of the following statements is the most important for the nurse to include in the teaching?

Correct Answer is C

Explanation

A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil (Viagra). He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?

A woman asks the nurse, "How do oral contraceptives prevent pregnancy?" What will the nurse explain about the combination of estrogen and progesterone in oral contraceptives?

A nurse at a family practice clinic receives a call from a client who is prescribed oral contraceptives but forgot to take one dose. The client reports she is in the first week of a 28-day cycle pack. Which of the following instructions should the nurse provide?

The nurse is preparing a community education program on preventive health care for women. What common screening test will the nurse plan on explaining to the women attending the program?

A nurse is providing care to a school-aged child with tetralogy of Fallot. The caregivers ask the nurse if there are any mental health concerns associated with this condition that they should be aware of. Which of the following statements made by the nurse is appropriate?

The nurse instructs a woman taking oral contraceptives to report which possible side effects? (Select all that apply.)

The nurse tells a woman who is trying to conceive to check her cervical mucus for changes. What will she expect the characteristic of cervical mucus to be a few days before ovulation?

The nurse is educating a woman diagnosed with premenstrual dysphoric disorder (PMDD). What is the best type of diet for the nurse to recommend?