A client is receiving high doses of methotrexate and is experiencing severe bone marrow suppression. The nurse expects which intervention to be ordered with this drug to reduce this problem?
Therapy with filgrastim
Leucovorin rescue
A transfusion of whole blood
Administration of allopurinol
The Correct Answer is B
B. methotrexate is a dihydrofolate reductase inhibitor which inhibits synthesis of building block for DNA synthesis and repair
A. Filgrastim is a growth factor used to boost neutrophil production
C. Transfusion-maybe necessary in the case of severe anemia
D. Allopurinol is an anti-uricemic agent used in gout
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
C. Red blood cells carry oxygen to the body tissue to provide energy
A. White blood cells fight infections
B. Albumin is a protein synthesized by the liver-unaffected by chemotherapy
D. Platelets are used for blood clotting
Correct Answer is C
Explanation
C. nasal decongestants cause vasoconstriction to reduce blood flow and secretions. On wearing off, the vessels dilate causing rebound nasal congestion
A. Oral formulation is less potent
B. Oral formulation have longer duration of effect that could cause systemic side effects
D. nasal sprays have immediate action as they bypass metabolism
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