A client ordered grapefruit juice for breakfast. The nurse should review the client's medication record for medications metabolized by the:
Gall bladder
Liver
Kidney
Small bowel
The Correct Answer is B
B. Liver: Grapefruit juice inhibits CYP3A4 enzymes in the liver, which metabolize many drugs (e.g., statins, calcium channel blockers). This inhibition can lead to increased drug levels and toxicity.
A. Gall bladder – The gall bladder stores bile but does not metabolize drugs.
C. Kidney – The kidneys excrete drugs, but grapefruit juice does not significantly impact renal metabolism.
D. Small bowel – Some drug metabolism occurs in the intestines, but grapefruit juice primarily affects liver enzymes.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Baked chicken: Safe if properly cooked, as heat kills bacteria.
B. Fresh fruit basket: A WBC count of 2,200/mm³ indicates neutropenia, increasing the risk of infections. Fresh fruits (unless thoroughly washed or peeled) may contain bacteria or fungi, posing an infection risk.
C. A factory-sealed box of chocolates: Sealed items reduce the risk of contamination.
D. Bagels: Processed and baked, so unlikely to carry harmful bacteria.
Correct Answer is D
Explanation
A. Tachypnea and hypotension: Tachypnea means fast breathing, but the client has slow breathing.
B. Tachypnea and hypertension: Tachypnea (fast breathing) and hypertension (high blood pressure) do not match the client’s symptoms.
C. Bradypnea and hypertension: Bradypnea (slow breathing) is correct, but hypertension (high BP) is incorrect because the client has low BP (hypotension).
D. Bradypnea and hypotension: Bradypnea means slow breathing, and hypotension means low blood pressure, both of which match the symptoms of a drug overdose (e.g., opioid overdose).
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