A client ordered grapefruit juice for breakfast. The nurse should review the client's medication record for medications metabolized by the:
Gall bladder
Liver
Kidney
Small bowel
The Correct Answer is B
B. Liver: Grapefruit juice inhibits CYP3A4 enzymes in the liver, which metabolize many drugs (e.g., statins, calcium channel blockers). This inhibition can lead to increased drug levels and toxicity.
A. Gall bladder – The gall bladder stores bile but does not metabolize drugs.
C. Kidney – The kidneys excrete drugs, but grapefruit juice does not significantly impact renal metabolism.
D. Small bowel – Some drug metabolism occurs in the intestines, but grapefruit juice primarily affects liver enzymes.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Intravenous: IV administration delivers medication directly into the bloodstream, allowing for the fastest onset of action (within seconds to minutes).
B. Topical patch: Slow absorption, designed for long-term, sustained release.
C. Sublingual: Faster than oral, but slower than IV (absorbed through mucous membranes).
D. Intramuscular: Faster than oral, but slower than IV, as the drug must diffuse into the bloodstream from muscle tissue.
Correct Answer is ["6750"]
Explanation
- 1 gram = 1000 mg
- 6.75 g × 1000 = 6750 mg
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