A client with an acute stroke must receive Alteplase (tissue plasminogen activator tPA) 0.9 mg/kg (maximum dose 90 mg) over 60 minutes. The client weighs 335 pounds. What dose should the client receive? (Use a preceding zero if necessary. Do not use trailing zeros. Round to the nearest tenth if necessary)
The Correct Answer is ["90"]
Step 1: Convert weight to kilograms
335 lb ÷ 2.2 = 152.3 kg
Step 2: Calculate the dose of Alteplase (tPA)
0.9 mg/kg × 152.3 kg = 137.1 mg
Step 3: Apply the maximum dose limit
The calculated dose (137.1 mg) exceeds the maximum allowed dose of 90 mg.
Therefore, the dose to administer is 90 mg.
Final Answer: 90 mg
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Muscle rigidity, flat affect, and bradykinesia: The hallmark symptoms of PD include:
Muscle rigidity: Stiffness or inflexibility in the muscles, often felt as resistance when the patient’s limbs are moved.
Flat affect: A reduced facial expression or lack of emotional expression, which is common in PD due to the difficulty in controlling facial muscles.
Bradykinesia: Slowness of movement, which makes initiating and completing voluntary movements more difficult. This is a major characteristic of PD.
B. Generalized weakness and fatigue: While weakness and fatigue can occur in PD, they are not considered the primary hallmark symptoms. The primary issues in PD are related to movement abnormalities, including tremor, rigidity, and bradykinesia. Fatigue can be secondary to the motor difficulties.
C. Ascending weakness starting in the legs: This is more characteristic of conditions like Guillain-Barré syndrome or other neurological disorders that cause progressive weakness, rather than PD. In PD, motor symptoms are typically bilateral and affect both sides of the body more symmetrically over time, not starting in the legs.
D. Increasing dementia and involuntary movements: While dementia can occur later in the course of PD, it is not a primary early symptom. Involuntary movements, such as tremors, can be a feature of PD but are not typically described as the same type of "involuntary movements" seen in conditions like Huntington's disease.
Correct Answer is D
Explanation
A. Urinary retention can occur in Guillain-Barre Syndrome due to autonomic dysfunction, but it is not the most life-threatening complication.
B. Hypertension may be seen as part of autonomic instability in GBS, but it is usually not the primary concern.
C. Hyperglycemia is not a typical complication of GBS itself, unless related to treatments like IV corticosteroids (which are not first-line therapy for GBS) or comorbid conditions.
D. Guillain-Barre Syndrome causes progressive ascending paralysis, which can eventually involve the respiratory muscles. Monitoring for respiratory failure is critical, as it can develop rapidly and requires immediate intervention, such as mechanical ventilation.
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