A client with an acute stroke must receive Alteplase (tissue plasminogen activator tPA) 0.9 mg/kg (maximum dose 90 mg) over 60 minutes. The client weighs 335 pounds. What dose should the client receive? (Use a preceding zero if necessary. Do not use trailing zeros. Round to the nearest tenth if necessary)
The Correct Answer is ["90"]
Step 1: Convert weight to kilograms
335 lb ÷ 2.2 = 152.3 kg
Step 2: Calculate the dose of Alteplase (tPA)
0.9 mg/kg × 152.3 kg = 137.1 mg
Step 3: Apply the maximum dose limit
The calculated dose (137.1 mg) exceeds the maximum allowed dose of 90 mg.
Therefore, the dose to administer is 90 mg.
Final Answer: 90 mg
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. The ABG results are pH 7.41, PaO2 93, PaCO2 35, and HCO3 24: These ABG values are all within normal ranges:
pH 7.35–7.45 (normal)
PaO2 80–100 mmHg (normal)
PaCO2 35–45 mmHg (normal)
HCO3 22–26 mEq/L (normal)
These results indicate stable respiratory function and do not warrant immediate intervention.
B. The client's pulse oximeter reading is 91% with a consistent waveform: While 91% is slightly lower than the ideal oxygen saturation (usually above 92%–94%), it is still above the critical threshold of 90%. This could be an acceptable level in some patients on a ventilator, particularly if there are no signs of distress or other abnormalities.
C. There is no manual resuscitation bag at the client's bedside: This is a critical situation. A manual resuscitation bag (Ambu bag) is essential for emergency resuscitation if the ventilator fails or if there is an unexpected issue with the patient's airway. Not having a manual resuscitation bag at the bedside is a safety concern that warrants immediate intervention, as it could delay life-saving measures in an emergency.
D. The patient is receiving continuous IV sedation at 150 mL/hr. There's currently 100 mL remaining of the infusion: While it's important to monitor IV sedation infusions, this situation does not immediately warrant intervention. The nurse can track the remaining infusion and ensure there is an adequate supply or order a new infusion if necessary.
Correct Answer is B
Explanation
A. Crushing sustained-release tablets is not recommended because doing so could interfere with the controlled release of the medication, which is designed to release slowly over time. This could lead to adverse effects.
B. Pyridostigmine is used to improve muscle strength in patients with Myasthenia Gravis (MG). Taking it 30-60 minutes before meals helps maximize its effect on muscle strength, particularly for activities like chewing and swallowing, which are often affected by MG.
C. Pyridostigmine is typically used regularly, not just as needed. Consistent dosing helps maintain muscle strength and manage the symptoms of MG, rather than only addressing occasional weakness and fatigue.
D. Doubling the dose without medical advice can be dangerous. The prescribed dose should be followed, and any changes should be discussed with a healthcare provider to avoid potential overdose or side effects.
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