A client with hepatitis C has been experiencing symptoms of gastroesophageal reflux.
What H antagonist would be most appropriate for this client’s needs?
Nizatidine.
Ranitidine.
Cimetidine.
Famotidine.
The Correct Answer is D
Famotidine is a histamine type 2 receptor antagonist (H blocker) which is commonly used for treatment of acid-peptic disease and heartburn. Famotidine has been linked to rare instances of clinically apparent acute liver injury, but it is less likely to cause hepatotoxicity than cimetidine, another H blocker. Famotidine also has fewer drug interactions than cimetidine.
Choice A is wrong because nizatidine is another H blocker that can cause mild and transient serum aminotransferase elevations.
Nizatidine has not been linked to cases of clinically apparent liver injury, but it has not been widely used.
Choice B is wrong because ranitidine is another H blocker that can cause mild and transient serum aminotransferase elevations.
Ranitidine has also been associated with rare instances of clinically apparent liver injury, some of which were fatal or required liver transplantation.
Choice C is wrong because cimetidine is another H blocker that can cause mild and transient serum aminotransferase elevations.
Cimetidine has also been implicated in several cases of clinically apparent acute liver injury, some of which were severe and led to acute liver failure and death.
Cimetidine also has many drug interactions due to its inhibition of cytochrome P enzymes.
Normal ranges for serum aminotransferases are 7 to 56 U/L for alanine aminotransferase (ALT) and 10 to 40 U/L for as
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Levothyroxine is a synthetic thyroid hormone that is used to treat hypothyroidism. It should be taken on an empty stomach, preferably in the morning, with a full glass of water to facilitate absorption and prevent choking. Taking the medication with food or other substances may interfere with its effectiveness.
Choice A is wrong because levothyroxine does not need to be taken after breakfast.
In fact, taking it after breakfast may reduce its absorption and efficacy.
Choice C is wrong because levothyroxine does not require the patient to remain in the upright position for 30 minutes after administering.
This instruction is more applicable to bisphosphonates, which are drugs used to treat osteoporosis.
Choice D is wrong because levothyroxine should not be taken at night.
Taking it at night may cause insomnia, as well as reduced absorption and efficacy.
Correct Answer is B
Explanation
This is because antiemetics should be given to prevent motion sickness rather than after nausea or vomiting develop. Taking the medication 30 minutes before departing allows enough time for the drug to be absorbed and reach its peak effect.
Choice A is wrong because avoiding eating or drinking for 6 hours before the trip may cause dehydration and low blood sugar, which can worsen nausea and vomiting.
It is better to eat a light meal or snack before the trip and avoid spicy, greasy, or acidic foods.
Choice C is wrong because taking two doses if relief is not achieved may cause overdose and adverse effects.
Antiemetics should be taken as prescribed and not exceeded without consulting a doctor.
Choice D is wrong because increasing fluid intake to prevent urinary retention is not relevant for motion sickness.
Urinary retention is a possible side effect of some antiemetics, such as anticholinergics, but it is not a common problem for most people.
Fluid intake should be moderate and not excessive to avoid stomach distension.
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