A nurse is caring for a child who has a penicillin allergy.
Which of the following prescriptions should the nurse verify with the provider?
Erythromycin
Amphotericin B
Amoxicillin-clavulanate
Gentamicin
Choice D rationale:
The Correct Answer is C
Choice A rationale:
Erythromycin Erythromycin is a macrolide antibiotic that is often used as an alternative to penicillin. It is generally safe for use in patients with a penicillin allergy. It works by inhibiting bacterial protein synthesis and is effective against a wide range of bacteria.
Choice B rationale:
Amphotericin B Amphotericin B is an antifungal medication, not an antibiotic. It is used to treat serious, systemic fungal infections. It has no cross-reactivity with penicillin, so it would not be a concern for a patient with a penicillin allergy.
Choice C rationale:
Amoxicillin-clavulanate Amoxicillin-clavulanate is a type of penicillin antibiotic. Patients with a known penicillin allergy should avoid this medication, as they may have a cross-reactivity to it. This is why the nurse should verify this prescription with the provider.
Choice D rationale:
Gentamicin Gentamicin is an aminoglycoside antibiotic used to treat serious bacterial infections caused by gram-negative bacteria. It is not related to penicillin and would be safe for a patient with a penicillin allergy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C"]
Explanation
Choice A rationale:
This statement is incorrect. Sulfonamides should be taken for the full time of treatment, even if the patient begins to feel better after a few days. If the medication is stopped too soon, the symptoms may return.
Choice B rationale:
This statement is correct. Sulfonamides can cause increased photosensitivity, which means the skin can be more sensitive to the sun and burn more easily. Therefore, patients should be educated to use sunscreen and protective clothing with sun exposure.
Choice C rationale:
This statement is correct. Sulfonamides are best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by the doctor. Drinking extra water will help to prevent some unwanted effects of sulfonamides.
Choice D rationale:
This statement is incorrect. Restricting daily fluid intake to 1000ml per day while on sulfonamides could increase the risk of crystalluria that can cause kidney stones or decreased kidney function. Therefore, patients should increase their water intake while taking these medications.
Correct Answer is C
Explanation
Choice A rationale:
Proton pump inhibitors (PPIs) are used extensively for the treatment of gastric acid-related disorders, often over the long term, which raises the potential for clinically significant drug interactions in patients receiving concomitant medications.
However, there is no specific mention of a significant interaction between PPIs and aminoglycosides.
Choice B rationale:
Aminoglycoside antibiotics and calcium channel blockers can interact at the neuromuscular junctions. This interaction is of clinical significance because when these agents are given concurrently during the perioperative period they may lead to respiratory depression or prolonged apnea. However, this is not directly related to the therapeutic effect of aminoglycosides, but rather a side effect of their combined use.
Choice C rationale:
The loop-diuretics (ethacrynic acid, furosemide, bumetamide) and aminoglycoside antibiotics (kanamycin, gentamicin, tobramycin, amikacin, etc.) are important drugs frequently used to treat seriously ill patients. Not uncommonly both types of drugs are given to the same patient exposing that patient to the risk of a hearing loss (ototoxicity)5. In addition, the risk of ototoxicity could be enhanced by the concomitant use of loop diuretics and aminoglycoside antibiotics.
Choice D rationale:
Phenytoin is a medication used to treat seizures. It has a complex pharmacokinetic profile and can interact with many other drugs. However, there is no specific mention of a significant interaction between phenytoin and aminoglycosides.
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