A nurse is caring for a client with OCD who is taking fluoxetine (Prozac). The nurse should monitor the client for which adverse effect of this medication?

Bupropion (Wellbutrin) is an antidepressant that works by increasing the levels of dopamine and norepinephrine in your brain. These are neurotransmitters that regulate mood, motivation, and reward.By increasing their levels, bupropion can help improve your symptoms of depression.

Choice A is wrong because it describes the mechanism of action of selective serotonin and norepinephrine reuptake inhibitors (SNRIs), such as venlafaxine (Effexor) or duloxetine (Cymbalta).These drugs block the reuptake of serotonin and norepinephrine, making more of them available in the synaptic cleft.

Choice C is wrong because it describes the mechanism of action of monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil) or tranylcypromine (Parnate). These drugs inhibit the breakdown of serotonin and norepinephrine, as well as dopamine and tyramine, by the enzyme monoamine oxidase.This increases their levels in the brain, but also poses a risk of hypertensive crisis if the client consumes foods high in tyramine.

Choice D is wrong because it describes the mechanism of action of benzodiazepines, such as diazepam (Valium) or alprazolam (Xanax). These drugs enhance the activity of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter that reduces anxiety and induces relaxation.However, these drugs are not used to treat depression, and can cause dependence and withdrawal symptoms.

This is because fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI) that can increase the level of serotonin in the brain. Serotonin syndrome is a potentially life-threatening condition that occurs when there is too much serotonin in the body. It can cause symptoms such as agitation, confusion, tremors, muscle rigidity, fever, and seizures.

Choice A is wrong because extrapyramidal symptoms are more commonly associated with antipsychotic medications, not SSRIs. Extrapyramidal symptoms include involuntary movements, muscle spasms, and restlessness.

Choice C is wrong because neuroleptic malignant syndrome is a rare but serious reaction to antipsychotic medications, not SSRIs. Neuroleptic malignant syndrome causes high fever, muscle rigidity, altered mental status, and autonomic instability.

Choice D is wrong because anticholinergic crisis is a result of excessive blockade of acetylcholine receptors by medications such as antihistamines, tricyclic antidepressants, and antiparkinsonian drugs. Anticholinergic crisis can cause dry mouth, blurred vision, urinary retention, constipation, tachycardia, and delirium.

The normal range of serotonin in the blood is 101 to 283 ng/mL.