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A nurse is educating a patient and their family about thrombocytopenia.
Which statement accurately describes the normal platelet count range?

"A normal platelet count is below 50,000/uL.”

"The normal platelet count range is 150,000/uL to 400,000/uL.”

"Platelet counts below 10,000/uL are considered normal.”

"A platelet count above 1,000,000/uL is typical in healthy individuals.”

Answer and Explanation

The Correct Answer is B

Choice A rationale:

"A normal platelet count is below 50,000/uL." Rationale: This statement is incorrect.

A platelet count below 50,000/uL is considered low and may indicate thrombocytopenia.

However, it is not within the normal range.

The normal platelet count range is higher.

Choice B rationale:

"The normal platelet count range is 150,000/uL to 400,000/uL." Rationale: This statement is accurate.

The normal platelet count range typically falls between 150,000/uL to 400,000/uL.

Platelets play a crucial role in blood clotting, and this range reflects the normal quantity needed for proper clot formation and prevention of excessive bleeding.

Choice C rationale:

"Platelet counts below 10,000/uL are considered normal." Rationale: This statement is incorrect.

A platelet count below 10,000/uL is extremely low and indicates severe thrombocytopenia.

It is not within the normal range.

Choice D rationale:

"A platelet count above 1,000,000/uL is typical in healthy individuals." Rationale: This statement is incorrect.

A platelet count above 1,000,000/uL is considered abnormally high and can lead to an increased risk of clot formation, which is not typical in healthy individuals.

The normal range is much lower.

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Correct Answer is B

Explanation

Choice A rationale:

"ITP results from decreased platelet production in the bone marrow." Rationale: This statement is not accurate.

Immune Thrombocytopenic Purpura (ITP) is primarily a disorder of platelet destruction, not decreased production in the bone marrow.

In ITP, autoantibodies target platelets, leading to their destruction by macrophages.

Choice B rationale:

"In ITP, autoantibodies mark platelets for destruction by macrophages." Rationale: This is the correct answer.

ITP is an autoimmune disorder where the immune system produces autoantibodies that attach to platelets, tagging them for destruction by macrophages in the spleen and liver.

Choice C rationale:

"ITP is characterized by impaired cleavage of von Willebrand factor." Rationale: This statement is not accurate.

Impaired cleavage of von Willebrand factor is a characteristic of von Willebrand disease, a different bleeding disorder, not ITP.

Choice D rationale:

"Thrombocytopenia in ITP is triggered by heparin-platelet factor 4 complexes." Rationale: This statement is incorrect.

Heparin-induced thrombocytopenia (HIT) involves the formation of antibodies against heparin-platelet factor 4 complexes, leading to platelet activation and a decrease in platelet count.

This is a different condition than ITP.

A. "Spontaneous bleeding in thrombocytopenia is due to excessive clotting.” B. "Immune-mediated destruction of platelets leads to spontaneous bleeding.” C. "Bleeding occurs in thrombocytopenia due to increased platelet production.” D. "Thrombocytopenia-related bleeding is a result of heparin therapy.”

Correct Answer is B

Explanation

Choice A rationale:

"Spontaneous bleeding in thrombocytopenia is due to excessive clotting." Rationale: This statement is not accurate.

Thrombocytopenia is characterized by a low platelet count, which impairs the blood's ability to form clots.

Spontaneous bleeding occurs because there are not enough platelets to participate in clot formation.

Choice B rationale:

"Immune-mediated destruction of platelets leads to spontaneous bleeding." Rationale: This is the correct answer.

In thrombocytopenia, especially immune thrombocytopenic purpura (ITP), the immune system destroys platelets, leading to a decreased platelet count.

This makes the patient more prone to spontaneous bleeding.

Choice C rationale:

"Bleeding occurs in thrombocytopenia due to increased platelet production." Rationale: This statement is incorrect.

Thrombocytopenia is characterized by a decreased platelet count, not increased production.

Choice D rationale:

"Thrombocytopenia-related bleeding is a result of heparin therapy." Rationale: This statement is inaccurate.

Thrombocytopenia related to heparin therapy is known as heparin-induced thrombocytopenia (HIT), and it occurs due to an immune response to heparin, not the same mechanism as in thrombocytopenia.

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A nurse is educating a patient and their family about thrombocytopenia.Which statement accurately describes the normal platelet count range?

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Naxlex Comprehensive Predictor Exams

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Explanation

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Correct Answer is B

Explanation

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A nurse is educating a patient and their family about thrombocytopenia.
Which statement accurately describes the normal platelet count range?