A nurse is monitoring a client who is at 29 weeks of gestation and has pre-term labor.

The client is receiving magnesium sulfate IV infusion.

Which of the following are expected adverse effects of this medication? (Select all that apply)

Creatinine clearance.

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis and suppresses uterine contractions.However, it can also causerenal failurein the fetus and the mother by reducing renal blood flow and glomerular filtration rate.

Therefore, the nurse should monitor the creatinine clearance, which is a measure of renal function, while the client is receiving this medication.

Choice A is wrong because indomethacin does not affect platelet count or coagulation.

Choice C is wrong because indomethacin does not affect liver function tests.

Choice D is wrong because indomethacin does not affect blood glucose levels.

Normal ranges for creatinine clearance are 88-128 mL/min for women and 97-137 mL/min for men.Normal ranges for platelet count are 150,000-450,000 cells/mm3.

Normal ranges for liver function tests vary depending on the specific test, but some common ones are: alanine aminotransferase (ALT) 7-55 U/L, aspartate aminotransferase (AST) 8-48 U/L, alkaline phosphatase (ALP) 45-115 U/L, total bilirubin 0.1-1.2 mg/dL.

Prepare for an emergency cesarean section.This is because the client has pre-term labor that has not responded to tocolytic therapy, which are drugs that are used to delay delivery for a short time.The client’s cervix is dilated to 4 cm and she is experiencing regular contractions every 3 minutes, which are signs of active labor.The baby is at 33 weeks of gestation, which is premature and may have complications such as respiratory distress syndrome or bleeding in the brain.

Therefore, the client needs an emergency cesarean section to deliver the baby as soon as possible and prevent further risks.

Choice A is wrong because administering magnesium sulfate intravenously is a type of tocolytic therapy that the client has already failed.Magnesium sulfate may also have side effects such as nausea, vomiting, flushing, headache, and muscle weakness.

Choice C is wrong because placing the client in Trendelenburg position, which is lying on the back with the feet elevated above the head, is not recommended for preterm labor.This position may increase the risk of aspiration, decrease cardiac output, and impair gas exchange.

Choice D is wrong because administering antibiotics prophylactically is not indicated for preterm labor unless there is evidence of infection in the uterus or membranes.

Antibiotics may also cause allergic reactions or bacterial resistance