A nurse is planning to administer medications to a client who weighs 198 lb. The prescription reads, "filgrastim 5 mcg/kg, subcutaneous, daily." Available is filgrastim 300 mcg/mL. How many mL should the nurse plan to give with each dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Answer and Explanation

The Correct Answer is ["1.5"]

Convert the client's weight from pounds to kilograms by dividing by 2.2. 198 lb / 2.2 = 90 kg

Calculate the dose of filgrastim in micrograms by multiplying the client's weight in kilograms by the prescribed dose per kilogram. 90 kg x 5 mcg/kg = 450 mcg

Calculate the volume of filgrastim in milliliters by dividing the dose in micrograms by the concentration of the available solution. 450 mcg / 300 mcg/mL = 1.5 mL

Round the answer to the nearest tenth. The nurse should plan to give 1.5 mL of filgrastim with each dose.

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Correct Answer is C

Explanation

A. An increased heart rate can be a sign of dehydration and would not indicate that IV fluid replacement has been effective.
B. Excessive thirst is a symptom of dehydration and would not indicate that IV fluid replacement has been effective.
C. Moist oral mucous membranes indicate improved hydration status and are a positive response to IV fluid replacement.
D. Decreased blood pressure is a sign of dehydration and would not indicate that IV fluid replacement has been effective.

A. "I can take my medication in the morning with my coffee." B. “I should limit my fluid intake while on this medication." C. “I may sprinkle the medication in applesauce." D. "I will need to have blood levels drawn."

Correct Answer is D

Explanation

A. Taking theophylline with coffee may increase its absorption and risk of adverse effects due to caffeine's effects on metabolism, so this statement is not appropriate.
B. Theophylline is a bronchodilator that may cause dehydration as a side effect, so limiting fluid intake is not recommended.
C. Theophylline sustained-release capsules should not be opened, crushed, or chewed, as it can alter the drug's release characteristics and increase the risk of adverse effects.

D. Monitoring blood levels of theophylline is essential to ensure therapeutic effectiveness and avoid toxicity, so the client's understanding of the need for blood level monitoring indicates comprehension of the teaching.

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Naxlex Comprehensive Predictor Exams

A nurse is caring for a client who is dehydrated and receiving IV fluid replacement. The nurse should identify that which of the following findings indicates the treatment has been effective?

Correct Answer is C

Explanation

A nurse is providing teaching to a client who has a new prescription for theophylline, a sustained-release capsule. Which of the following statements by the client indicates an understanding of the teaching?

Correct Answer is D

Explanation

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