A nurse is preparing to administer naloxone 0.2 mg IM to client. Available is naloxone injection 0.4 mg/mL. How many ml. should the nurse administer? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use trailing zero.)

A) Clonazepam 0.5 mg PO three times daily: This prescription is appropriate. Clonazepam, a benzodiazepine, is often used for short-term management of anxiety or agitation, which can be associated with manic episodes. The prescribed dose of 0.5 mg three times daily is within the typical therapeutic range and is commonly used in the acute management of mania.

B) Lithium 300 mg PO three times daily: This prescription is appropriate. Lithium is a first-line medication used to treat mania in bipolar disorder. The prescribed dose of 300 mg three times daily falls within the typical dosing range for managing mania. Lithium requires regular blood level monitoring due to its narrow therapeutic window, but the prescription itself is reasonable.
C) Risperidone 3.0 mg PO daily: This prescription is appropriate. Risperidone, an atypical antipsychotic, is commonly prescribed for the management of mania or psychosis in bipolar disorder. The prescribed dose of 3.0 mg daily is within the usual therapeutic range and is often effective for controlling symptoms of mania.

D) Divalproex 1.5 g PO twice daily: This prescription should be clarified. The prescribed dose of 1.5 g twice daily is unusually high for divalproex, which is commonly used for mood stabilization in bipolar disorder. A more typical starting dose for divalproex would be 750 mg to 1 g daily, and it is usually titrated based on the client’s response and serum drug levels. A dose of 3 g daily could increase the risk of side effects, including hepatotoxicity and thrombocytopenia, and should be clarified with the provider.

A) Propranolol extended release 80 mg PO daily: This prescription is appropriate. Propranolol is a beta-blocker used for various conditions, such as hypertension, anxiety, and arrhythmias. The prescribed dose of 80 mg daily is within the standard dosage range for extended-release propranolol and is commonly prescribed for these conditions.

B) Sertraline 125 mg daily: This prescription should be clarified. The typical dosage for sertraline (a selective serotonin reuptake inhibitor, or SSRI) is 50–100 mg daily for most adults, with 125 mg being above the usual starting dose. While higher doses (up to 200 mg daily) are sometimes used, 125 mg daily is not typical and should be clarified with the provider to ensure it is correct.

C) Clonidine transdermal 0.1 mg/24 hr apply every 7 days: This prescription is appropriate. Clonidine is used to treat hypertension, and the 0.1 mg/24 hr transdermal patch is commonly prescribed, applied every 7 days. This is a standard dosing regimen for the transdermal formulation.

D) Pantoprazole 40 mg PO BID: This prescription is appropriate. Pantoprazole, a proton pump inhibitor (PPI), is typically dosed at 40 mg twice daily (BID) for conditions like gastroesophageal reflux disease (GERD) or peptic ulcers. The prescribed dose and frequency are consistent with common clinical practice for more severe cases.