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A nurse is preparing to administer perphenazine 0.032 g PO divided in four equal doses daily to a client who has psychosis. Available is perphenazine oral solution 16 mg/5 mL. How many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Answer and Explanation

The Correct Answer is ["2.5"]

Step by step calculation:

Determine the total daily dosage in grams: 0.032 g

Convert grams to milligrams:

0.032 g×1000 mg/g=32 mg

Divide the total daily dose into four equal doses:

Dose per administration=32 mg/4=8 mg

Determine the concentration available: 16 mg/5 mL

Use the formula:

Volume (mL)=Required dose/(mg)Concentration (mg/mL)

First, find the mg/mL concentration:

16 mg/5 mL=3.2 mg/mL

Now calculate the volume:

Volume (mL)=8 mg/3.2 mg/mL

Volume (mL)=2.5

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Correct Answer is ["2.5"]

Explanation

Step by step calculation:

Determinethetotaldailydosageingrams:0.032g

Convertgramstomilligrams:

0.032g×1000mg/g=32mg

Dividethetotaldailydoseintofourequaldoses:

Doseperadministration=32mg/4=8mg

Determinetheconcentrationavailable:16mg/5mL

Usetheformula:

Volume(mL)=Requireddose/(mg)Concentration(mg/mL)

First,findthemg/mLconcentration:

16mg/5mL=3.2mg/mL

Nowcalculatethevolume:

Volume(mL)=8mg/3.2mg/mL

Volume(mL)=2.5

A. Dissolve the tablet in 118 mL (4 oz) liquid. B. Have the client chew the medication before swallowing. C. Mix the medication in 5 mL (1 tsp) soft food. D. Place the tablet between the client's cheek and gums.

Correct Answer is D

Explanation

A. Dissolve the tablet in 118 mL (4 oz) liquid: This option is incorrect because buccal tablets are specifically designed to dissolve in the mouth without liquid. Using liquid can dilute the medication and hinder effective absorption.

B. Have the client chew the medication before swallowing: Chewing the buccal tablet is not appropriate, as it can lead to rapid release and loss of the intended slow absorption through the mucous membranes. This method undermines the effectiveness of the medication.

C. Mix the medication in 5 mL (1 tsp) soft food: This action is also incorrect, as mixing the buccal tablet with food may interfere with its absorption. Buccal medications are intended to dissolve between the cheek and gums for optimal effect.

D. Place the tablet between the client's cheek and gums: This is the correct method for administering a buccal tablet. This placement allows the medication to dissolve slowly and be absorbed effectively through the buccal mucosa, providing the desired therapeutic effect.

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