A nurse is providing education about leukemia to a group of nursing students. Which statement by a student indicates a correct understanding of the pathophysiology of leukemia?
"Leukemia arises from the uncontrolled growth and division of normal blood cells."
"In leukemia, cancerous cells infiltrate and replace healthy tissues in organs such as the liver and lungs."
"The genetic mutations in leukemia result in the formation of abnormal blood cells in the lymph nodes."
"The pathophysiology of leukemia involves the abnormal proliferation of bone marrow stem cells."
The Correct Answer is D
A) This choice is incorrect because leukemia arises from the uncontrolled growth and division of abnormal blood cells, not normal blood cells. These abnormal cells disrupt the normal functioning of the blood and bone marrow.
B) This choice is incorrect because while cancerous cells may infiltrate and replace healthy tissues in other types of cancer, leukemia primarily affects the bone marrow and blood, not other organs like the liver and lungs.
C) This choice is incorrect because while leukemia does involve genetic mutations, the formation of abnormal blood cells primarily occurs within the bone marrow, not in the lymph nodes.
D) This choice is correct. The pathophysiology of leukemia involves the abnormal proliferation and differentiation of bone marrow stem cells. These cells undergo genetic mutations, leading to the development of leukemia and the production of abnormal blood cells.
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Related Questions
Correct Answer is D
Explanation
A) This choice is incorrect because while a complete blood count (CBC) is an important initial screening test for leukemia, it alone is not definitive for diagnosis. A CBC may show abnormal levels of blood cells, prompting further investigation, including a bone marrow biopsy.
B) This choice is incorrect because a urinalysis is not used to diagnose leukemia. It is a test used to evaluate kidney function and detect urinary abnormalities.
C) This choice is incorrect because a chest X-ray is not a definitive diagnostic tool for leukemia. It is primarily used to assess the lungs and chest organs for conditions such as pneumonia or tumors.
D) This choice is correct. A bone marrow biopsy is a definitive diagnostic tool to confirm leukemia. In this procedure, a small sample of bone marrow is taken from the hipbone or breastbone and examined under a microscope to determine if leukemia cells are present. It allows for the identification of abnormal cells in the bone marrow, helping to establish the diagnosis and type of leukemia.
Correct Answer is B
Explanation
A) This choice is incorrect because impaired bone density would not directly cause ecchymoses on the skin. It might lead to an increased risk of fractures, but not bruising.
B) This choice is correct. Ecchymoses (bruises) of varying sizes with minimal trauma are common in leukemia due to a deficiency of platelets and impaired clotting factors in the blood. Leukemia can lead to decreased platelet production and clotting abnormalities, resulting in easy bleeding and bruising.
C) This choice is incorrect because increased production of platelets would improve clotting abilities and reduce the risk of ecchymoses.
D) This choice is incorrect because elevated levels of red blood cells would not directly cause ecchymoses on the skin. It may lead to other symptoms like increased blood viscosity.
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