A nurse is reinforcing teaching for a client who has type 2 diabetes mellitus and is prescribed glipizide. The client should be taught that glipizide works in which of the following ways?
Glipizide blocks glucose production in the liver.
Glipizide stimulates the pancreas to release adequate insulin.
Glipizide promotes the breakdown of glycogen to glucose.
Glipizide slows gastric emptying and decreases appetite.
The Correct Answer is B
A. Glipizide blocks glucose production in the liver: That is more the action of biguanides (metformin) affecting hepatic gluconeogenesis.
B. Glipizide stimulates the pancreas to release adequate insulin: Glipizide is a sulfonylurea that increases insulin release from pancreatic β-cells.
C. Glipizide promotes the breakdown of glycogen to glucose: That would raise blood glucose; glipizide does the opposite by increasing insulin.
D. Glipizide slows gastric emptying and decreases appetite: That is the mechanism of some GLP-1 agonists, not sulfonylureas.
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Related Questions
Correct Answer is D
Explanation
A. Bumetanide and diltiazem: Generally acceptable -a loop diuretic (bumetanide) plus a calcium-channel blocker (diltiazem) are from different classes and may be combined if clinically indicated (monitoring required).
B. Metolazone and valsartan: Use with caution -this combination (a thiazide-like diuretic and an ARB) is sometimes used but requires monitoring of electrolytes and renal function (risk of potassium/volume/electrolyte changes); not an automatic contraindication.
C. Captopril and furosemide: Commonly used together -an ACE inhibitor plus a loop diuretic is a frequently used and accepted combination for hypertension/volume control (monitor blood pressure and renal function).
D. Atenolol and metoprolol: Both are β-blockers (same pharmacologic class). Prescribing two cardioselective β-blockers concurrently is generally inappropriate (redundant and increases risk of bradycardia, hypotension and other adverse effects); the nurse should question this order.
Correct Answer is ["1"]
Explanation
Ordered: Synthroid 100 mcg = 100 micrograms.
Supplied: 0.1 mg/tablet.
Convert: 0.1 mg = 100 mcg.
Therefore, 100 mcg = 1 tablet.
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